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» Authors » M C Terencio

M C Terencio

Explore the profile of M C Terencio including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 36
Citations 295
Followers 0
Related Specialties
Pharmacology
Biochemistry
Biology
Top 10 Co-Authors
M J Alcaraz
M Paya
M L Ferrandiz
M J Sanz
A Ubeda
S De Rosa
B Gil
I Rioja
J N Dominguez
I Posadas
Published In
Life Sci
Eur J Pharmacol
J Ethnopharmacol
Naunyn Schmiedebergs Arch Pharmacol
Pharmazie
Affiliations
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Recent Articles
1.
Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis
Ferrandiz M, Maicas N, Garcia-Arnandis I, Terencio M, Motterlini R, Devesa I, et al.
Ann Rheum Dis . 2007 Dec; 67(9):1211-7. PMID: 18063671
Objective: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). Methods: Arthritis was induced in DBA-1/J...
2.
Antipsoriatic effects of avarol-3'-thiosalicylate are mediated by inhibition of TNF-alpha generation and NF-kappaB activation in mouse skin
Amigo M, Paya M, De Rosa S, Terencio M
Br J Pharmacol . 2007 Jul; 152(3):353-65. PMID: 17641670
Background And Purpose: Avarol is a marine sesquiterpenoid hydroquinone with anti-inflammatory and antipsoriatic properties. The aim of this study was to evaluate the in vitro and in vivo pharmacological behaviour...
3.
Evaluation of the anti-inflammatory and analgesic activity of Me-UCH9, a dual cyclooxygenase-2/5-lipoxygenase inhibitor
Araico A, Terencio M, Alcaraz M, Dominguez J, Leon C, Ferrandiz M
Life Sci . 2007 May; 80(23):2108-2117. PMID: 17490689
Recently, we reported the dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) activity by some phenylsulphonyl urenyl chalcone derivatives. 2,4-dichloro-4'N[N'(4''methylphenylsulphonyl)urenyl] chalcone (Me-UCH9), was selected in the present study to determine...
4.
Phenylsulphonyl urenyl chalcone derivatives as dual inhibitors of cyclo-oxygenase-2 and 5-lipoxygenase
Araico A, Terencio M, Alcaraz M, Dominguez J, Leon C, Ferrandiz M
Life Sci . 2005 Dec; 78(25):2911-8. PMID: 16360707
Two series of phenylsulphonyl urenyl chalcone derivatives (UCH) with various patterns of substitution were tested for their effects on nitric oxide (NO) and prostaglandin E2 (PGE2) overproduction in RAW 264.7...
5.
A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats
de Leon E, Alcaraz M, Dominguez J, Charris J, Terencio M
J Pharm Pharmacol . 2003 Nov; 55(9):1313-21. PMID: 14604476
The synthetic chalcone derivative 1-(2,4-dichlorophenyl)-3-(3-(6,7-dimethoxy-2-chloroquinolinyl))-2-propen-1-one (ClDQ) was evaluated for its anti-inflammatory, analgesic and immunomodulatory efficacy in-vitro and in-vivo. ClDQ concentration-dependently inhibited the production of nitric oxide (NO) (IC50 4.3 microM)...
6.
1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one, a chalcone derivative with analgesic, anti-inflammatory and immunomodulatory properties
de Leon E, Alcaraz M, Dominguez J, Charris J, Terencio M
Inflamm Res . 2003 Jul; 52(6):246-57. PMID: 12835896
Objective And Design: The synthetic chalcone derivative 1-(2,3,4-trimethoxyphenyl)-3-(3-(2-chloroquinolinyl))-2-propen-1-one (TQ) was evaluated for its immunomodulatory and anti-inflammatory efficacy in vitro and in vivo. Material And Subjects: Human neutrophils and lymphocytes from...
7.
Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives
Molina P, Tarraga A, Rioja I, Ubeda A, Terencio M, Alcaraz M
J Nat Prod . 2001 Oct; 64(10):1297-300. PMID: 11678654
The alkaloid isaindigotone (1a) and seven derivatives have been synthesized to study their influence on several leukocyte functions and the generation of inflammatory mediators. Isaindigotone (1a) was found to be...
8.
Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte formations and experimental inflammation
Molina P, Aller E, Lorenzo A, Rioja I, Ubeda A, Terencio M, et al.
J Med Chem . 2001 Apr; 44(6):1011-4. PMID: 11300882
A number of pyrido[1,2-c]pyrimidines bearing a nitrogen, oxygen, or sulfur functionality at C-1 were synthesized on solid-phase using the iminophosphorane methodology and tested for their effects on leukocyte functions in...
9.
Inhibition of 5-lipoxygenase activity by the natural anti-inflammatory compound aethiopinone
Benrezzouk R, Terencio M, Ferrandiz M, Hernandez-Perez M, Rabanal R, Alcaraz M
Inflamm Res . 2001 Apr; 50(2):96-101. PMID: 11289660
Objective And Design: We have investigated the mechanisms of action of aethiopinone, an anti-inflammatory compound from Salvia aethiopis L. roots. Material And Subjects: Human neutrophils from healthy volunteers and murine...
10.
Dysidotronic acid, a new sesquiterpenoid, inhibits cytokine production and the expression of nitric oxide synthase
Posadas I, Terencio M, Giannini C, DAuria M, Paya M
Eur J Pharmacol . 2001 Mar; 415(2-3):285-92. PMID: 11275011
In a previous study, we reported a new bioactive sesquiterpenoid, named dysidotronic acid, to be a potent, selective human synovial phospholipase A(2) inhibitor. Dysidotronic acid is a novel, non-complex manoalide...