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M C Ostrowski

Explore the profile of M C Ostrowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 1510
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Recent Articles
1.
Rudolph M, Sizemore S, Lu Y, Teng K, Basree M, Reinbolt R, et al.
Breast Cancer Res Treat . 2018 Feb; 169(3):457-467. PMID: 29464534
Purpose: High expression of glioma-associated oncogene homolog-1 (GLI1) is associated with poor prognosis in estrogen receptor (ER) positive breast cancers. We sought to define a GLI1-dependent gene signature in ER-positive...
2.
Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al.
Oncogene . 2017 Oct; 36(47):6658. PMID: 29035387
This corrects the article DOI: 10.1038/onc.2016.383.
3.
Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al.
Oncogene . 2016 Nov; 36(16):2297-2308. PMID: 27797378
Fibroblasts within the mammary tumor microenvironment are active participants in carcinogenesis mediating both tumor initiation and progression. Our group has previously demonstrated that genetic loss of phosphatase and tensin homolog...
4.
Trikha P, Sharma N, Pena C, Reyes A, Pecot T, Khurshid S, et al.
Oncogene . 2015 Nov; 35(28):3636-46. PMID: 26549026
The Rb-E2F axis is an important pathway involved in cell-cycle control that is deregulated in a number of cancers. E2f transcription factors have distinct roles in the control of cell...
5.
Mathsyaraja H, Thies K, Taffany D, Deighan C, Liu T, Yu L, et al.
Oncogene . 2014 Sep; 34(28):3651-61. PMID: 25241894
Metastasis of solid tumors is associated with poor prognosis and bleak survival rates. Tumor-infiltrating myeloid cells (TIMs) are known to promote metastasis, but the mechanisms underlying their collaboration with tumor...
6.
Bronisz A, Godlewski J, Wallace J, Merchant A, Nowicki M, Mathsyaraja H, et al.
Nat Cell Biol . 2011 Dec; 14(2):159-67. PMID: 22179046
PTEN (Phosphatase and tensin homolog deleted on chromosome 10) expression in stromal fibroblasts suppresses epithelial mammary tumours, but the underlying molecular mechanisms remain unknown. Using proteomic and expression profiling, we...
7.
Anghelina M, Moldovan L, Zabuawala T, Ostrowski M, Moldovan N
J Cell Mol Med . 2006 Sep; 10(3):708-15. PMID: 16989730
Objective: We have previously shown that monocytes/macrophages (MC/Mph) influence neovascularization by extracellular matrix degradation, and by direct incorporation into growing microvessels. To date, neither the phenotype of these cells, nor...
8.
Cassady A, Luchin A, Ostrowski M, Hume D
J Bone Miner Res . 2003 Oct; 18(10):1901-4. PMID: 14584903
The activity of the TRACP promoter has been investigated as a model of gene regulation in osteoclasts. The murine TRACP gene promoter contains potential binding sites for a number of...
9.
Luchin A, Suchting S, Merson T, Rosol T, Hume D, Cassady A, et al.
J Biol Chem . 2001 Aug; 276(39):36703-10. PMID: 11481336
The microphthalmia transcription factor (MITF), a basic-helix-loop-helix zipper factor, regulates distinct target genes in several cell types. We hypothesized that interaction with the Ets family factor PU.1, whose expression is...
10.
Smith J, Schaffner A, Hofmeister J, Hartman M, Wei G, Forsthoefel D, et al.
Mol Cell Biol . 2000 Oct; 20(21):8026-34. PMID: 11027273
The transcription factor ets-2 was phosphorylated at residue threonine 72 in a colony-stimulating factor 1 (CSF-1)- and mitogen-activated protein kinase-independent manner in macrophages isolated from motheaten-viable (me-v) mice. The CSF-1...