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M Benkirane

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Articles 38
Citations 1097
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Recent Articles
11.
Reynes J, Portales P, Segondy M, Baillat V, Andre P, Reant B, et al.
J Infect Dis . 2000 Mar; 181(3):927-32. PMID: 10720514
The intensity of expression of the chemokine receptor CCR5 is involved in in vitro cell infectability by human immunodeficiency virus (HIV)-1 R5 isolates. Because CCR5 expression varies among individuals, the...
12.
Kiernan R, Vanhulle C, Schiltz L, Adam E, Xiao H, Maudoux F, et al.
EMBO J . 1999 Nov; 18(21):6106-18. PMID: 10545121
The human immunodeficiency virus (HIV) trans- activator protein, Tat, stimulates transcription from the viral long-terminal repeats (LTR) through an RNA hairpin element, trans-activation responsive region (TAR). We and others have...
13.
Benkirane M, Chun R, Xiao H, Ogryzko V, Howard B, Nakatani Y, et al.
J Biol Chem . 1998 Sep; 273(38):24898-905. PMID: 9733796
A unique aspect of the retrovirus life cycle is the obligatory integration of the provirus into host cell chromosomes. Unlike viruses that do not integrate, retroviruses must conserve an ability...
14.
Xiao H, Neuveut C, Benkirane M, Jeang K
Biochem Biophys Res Commun . 1998 Mar; 244(2):384-9. PMID: 9514931
HIV-1 Tat has pleiotropic functions. While its most studied role is to activate transcription from the retroviral long terminal repeat (LTR)-promoter, Tat also has functions as a secretable growth factor,...
15.
Benkirane M, Jin D, Chun R, Koup R, Jeang K
J Biol Chem . 1998 Jan; 272(49):30603-6. PMID: 9388191
Human chemokine receptor 5 (CCR5) functions as a co-receptor for Human immunodeficiency virus (HIV-1) infection. CCR5 is a seven-transmembrane cell surface receptor. Recently, a naturally occurring mutation of CCR5, ccr5Delta32,...
16.
Benkirane M, Neuveut C, Chun R, Smith S, Samuel C, Gatignol A, et al.
EMBO J . 1997 Feb; 16(3):611-24. PMID: 9034343
TAR RNA binding protein (TRBP) belongs to an RNA binding protein family that includes the double-stranded RNA-activated protein kinase (PKR), Drosophila Staufen and Xenopus xlrbpa. One member of this family,...
17.
Briant L, Benkirane M, Girard M, Hirn M, Iosef C, Devaux C
J Virol . 1996 Aug; 70(8):5213-20. PMID: 8764030
A well-characterized mechanism by which anti-HLA class I monoclonal antibodies (MAb) inhibit human immunodeficiency virus type 1 (HIV-1) propagation in in vitro cell cultures is the neutralization of the virus...
18.
Briant L, Coudronniere N, Benkirane M, Devaux C
J Immunol . 1996 May; 156(10):3994-4004. PMID: 8621941
HIV-1-infected quiescent CD4+ cells harbor the virus in an inactive state until subsequent activation. The possibility that HIV-1 itself and the virus envelope glycoprotein 120 (gp120) might be important agents...
19.
Schmid-Antomarchi H, Benkirane M, Breittmayer V, Husson H, Ticchioni M, Devaux C, et al.
Eur J Immunol . 1996 Mar; 26(3):717-20. PMID: 8605943
T cell surface CD4 molecules act as co-receptors that amplify the T cell receptor (TcR)/CD3-induced signal transduction by a mechanism that requires the interaction of CD4 with p56lck tyrosine kinase...
20.
Benkirane M, Schmid-Antomarchi H, Littman D, Hirn M, Rossi B, Devaux C
J Virol . 1995 Nov; 69(11):6904-10. PMID: 7474107
Monoclonal antibodies (MAb) directed against the immunoglobulin complementary determining region 3 (CDR3)-like region of the CD4 molecule inhibit human immunodeficiency virus type 1 (HIV-1) transcription. We report here data showing...