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M Alexandrina Timoteo

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Articles 9
Citations 154
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Recent Articles
1.
Carneiro I, Timoteo M, Silva I, Vieira C, Baldaia C, Ferreirinha F, et al.
Br J Pharmacol . 2014 Apr; 171(14):3404-19. PMID: 24697602
Background And Purpose: Despite the abundant expression of the UDP-sensitive P2Y6 receptor in urothelial cells and sub-urothelial myofibroblasts its role in the control of bladder function is not well understood....
2.
Timoteo M, Carneiro I, Silva I, Noronha-Matos J, Ferreirinha F, Silva-Ramos M, et al.
Biochem Pharmacol . 2013 Nov; 87(2):371-9. PMID: 24269631
In contrast to the well-known signaling role of urothelial ATP to control bladder function, the hypothesis that uracil nucleotides (UTP and/or UDP) also exert autocrine/paracrine actions only recently gained experimental...
3.
Correia-de-Sa P, Adaes S, Timoteo M, Vieira C, Magalhaes-Cardoso T, Nascimento C, et al.
Auton Neurosci . 2006 Mar; 126-127:211-24. PMID: 16563876
Besides the well-characterized inhibitory effect of adenosine in the gastrointestinal tract mediated by A1 receptors, we recently demonstrated that endogenously generated adenosine facilitates [3H]acetylcholine release from myenteric neurons through preferential...
4.
Oliveira L, Timoteo M, Correia-de-Sa P
J Physiol . 2004 Aug; 560(Pt 1):157-68. PMID: 15297571
Motor nerve terminals possess multiple voltage-sensitive calcium channels operating acetylcholine (ACh) release. In this study, we investigated whether facilitation of neuromuscular transmission by adenosine generated during neuronal firing was operated...
5.
Duarte-Araujo M, Timoteo M, Correia-de-Sa P
Neurochem Int . 2004 Jul; 45(5):641-51. PMID: 15234106
In addition to the somatodendritic region, myenteric motoneuron terminals are endowed with nicotinic autoreceptors. We aimed at investigating the effect of nicotinic receptor (nAChR) activation on [3H]-acetylcholine ([3H]-ACh) release from...
6.
Duarte-Araujo M, Nascimento C, Timoteo M, Magalhaes-Cardoso T, Correia-de-Sa P
Br J Pharmacol . 2004 Mar; 141(6):925-34. PMID: 14993098
1. The coexistence of both inhibitory A(1) and facilitatory A(2) adenosine receptors in the rat myenteric plexus prompted the question of how adenosine activates each receptor subtype to regulate cholinergic...
7.
Faria M, Oliveira L, Timoteo M, Lobo M, Correia-de-Sa P
Synapse . 2003 May; 49(2):77-88. PMID: 12740863
Nicotinic receptor (nAChR) subtypes involved in pre- and postjunctional actions underlying tetanic fade were studied in rat phrenic-nerve hemidiaphragms. We investigated the ability of subtype-specific nAChR antagonists to depress nerve-evoked...
8.
Timoteo M, Faria M, Correia-de-Sa P
Eur J Pharmacol . 2003 Mar; 464(2-3):115-25. PMID: 12620503
We investigated the modulatory role of endogenous adenosine on tetanic-induced (50 Hz for 5 s) nicotinic facilitation of [3H]acetylcholine release (5 Hz for 50 s) from rat motoneurons. Adenosine deaminase...
9.
Oliveira L, Timoteo M, Correia-de-Sa P
Eur J Neurosci . 2002 Jun; 15(11):1728-36. PMID: 12081652
The crosstalk between adenosine and muscarinic autoreceptors regulating evoked [3H]-acetylcholine ([3H]-ACh) release was investigated on rat phrenic nerve-hemidiaphragm preparations. Motor nerve terminals possess facilitatory M1 and inhibitory M2 autoreceptors that...