Lydia M Contreras
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Explore the profile of Lydia M Contreras including associated specialties, affiliations and a list of published articles.
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65
Citations
672
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Recent Articles
1.
Lukasiewicz A, Leistra A, Hoefner L, Monzon E, Gode C, Zorn B, et al.
Front Mol Biosci
. 2025 Mar;
12:1493891.
PMID: 40051501
(PA) is a ubiquitous, Gram-negative, bacteria that can attribute its survivability to numerous sensing and signaling pathways; conferring fitness due to speed of response. Post-transcriptional regulation is an energy efficient...
2.
Rojano-Nisimura A, Miller L, Anantharaman A, Middleton A, Kibret E, Jung S, et al.
RNA Biol
. 2024 Nov;
21(1):13-30.
PMID: 39576267
General RNA chaperones are RNA-binding proteins (RBPs) that interact transiently and non-specifically with RNA substrates and assist in their folding into their native state. In bacteria, these chaperones impact both...
3.
Burroughs M, Sweet P, Contreras L
RNA Biol
. 2024 Nov;
21(1):132-148.
PMID: 39559912
Bulk increases in nucleobase oxidation, most commonly manifesting as the guanine (G) nucleobase modification 8-oxo-7,8-dihydroguanine (8-oxoG), have been linked to several disease pathologies. Elucidating the effects of RNA oxidation on...
4.
Contreras L, Belfort M
Proc Natl Acad Sci U S A
. 2024 Nov;
121(46):e2420445121.
PMID: 39495921
No abstract available.
5.
Simmons T, Partipilo G, Buchser R, Stankes A, Srivastava R, Chiu D, et al.
Nat Commun
. 2024 Oct;
15(1):8752.
PMID: 39384772
As synthetic biology expands, creating "drag-and-drop" regulatory tools that can achieve diverse regulatory outcomes are paramount. Herein, we develop a approach for engineering complex post-transcriptional control by rewiring the Carbon...
6.
Ekdahl A, Julien T, Suraj S, Kribelbauer J, Tavazoie S, Freddolino P, et al.
bioRxiv
. 2024 Jul;
PMID: 38979244
Recent research has indicated the presence of heterochromatin-like regions of extended protein occupancy and transcriptional silencing of bacterial genomes. We utilized an integrative approach to track chromatin structure and transcription...
7.
Cordova A, Niese B, Sweet P, Kamat P, Phillip J, Gordon V, et al.
Appl Environ Microbiol
. 2024 Jun;
90(7):e0010824.
PMID: 38864629
The extremophile maintains a highly organized and condensed nucleoid as its default state, possibly contributing to its high tolerance to ionizing radiation (IR). Previous studies of the nucleoid were limited...
8.
Rojano-Nisimura A, Grismore K, Ruzek J, Avila J, Contreras L
Microorganisms
. 2024 Apr;
12(4).
PMID: 38674581
Global rewiring of bacterial gene expressions in response to environmental cues is mediated by regulatory proteins such as the CsrA global regulator from Several direct mRNA and sRNA targets of...
9.
Taylor K, Miller L, Contreras L
Biochem Soc Trans
. 2024 Jan;
52(1):111-122.
PMID: 38174726
Cells encounter a variety of stresses throughout their lifetimes. Oxidative stress can occur via a myriad of factors, including exposure to chemical toxins or UV light. Importantly, these stressors induce...
10.
Engels S, Kamat P, Pafilis G, Li Y, Agrawal A, Haller D, et al.
PNAS Nexus
. 2023 Dec;
3(1):pgad415.
PMID: 38156290
Particulate matter (PM) is a ubiquitous component of air pollution that is epidemiologically linked to human pulmonary diseases. PM chemical composition varies widely, and the development of high-throughput experimental techniques...