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Lutz Schmitt

Explore the profile of Lutz Schmitt including associated specialties, affiliations and a list of published articles. Areas
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Articles 163
Citations 3196
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Recent Articles
1.
Gala Marti S, Wagner M, Nentwig L, Smits S, Schmitt L
Protein Sci . 2024 Sep; 33(10):e5181. PMID: 39312388
Pdr5 is the most abundant ABC transporter in Saccharomyces cerevisiae and plays a major role in the pleiotropic drug resistance (PDR) network, which actively prevents cell entry of a large...
2.
Anlauf M, Bilsing F, Reiners J, Spitz O, Hachani E, Smits S, et al.
Sci Rep . 2024 Apr; 14(1):8994. PMID: 38637678
Type I secretion systems (T1SS) facilitate the secretion of substrates in one step across both membranes of Gram-negative bacteria. A prime example is the hemolysin T1SS which secretes the toxin...
3.
Golin J, Schmitt L
Drug Resist Updat . 2023 Oct; 71:101010. PMID: 37862721
Pdr5 is a founding member of a large (pdr) subfamily of clinically and agriculturally significant fungal ABC transporters. The tremendous power of yeast genetics combined with biochemical and structural approaches...
4.
Lowe M, Hansch S, Hachani E, Schmitt L, Weidtkamp-Peters S, Kedrov A
Protein Sci . 2023 Oct; 32(11):e4797. PMID: 37779215
Biochemical processes within the living cell occur in a highly crowded environment, where macromolecules, first of all proteins and nucleic acids, occupy up to 30% of the volume. The phenomenon...
5.
Bork A, Smits S, Schmitt L
Biochim Biophys Acta Proteins Proteom . 2023 Sep; 1872(1):140967. PMID: 37757925
CBL1 is an EF hand Ca binding protein from A. thaliana that is involved in the detection of cellular Ca signals and the downstream signal transmission by interaction with the...
6.
Pourhassan Z, Cui H, Muckhoff N, Davari M, Smits S, Schwaneberg U, et al.
Appl Microbiol Biotechnol . 2023 Jul; 107(16):5131-5143. PMID: 37405436
Secretion of proteins into the extracellular space has great advantages for the production of recombinant proteins. Type 1 secretion systems (T1SS) are attractive candidates to be optimized for biotechnological applications,...
7.
Geyer J, Hofmann E, Schmitt L
Biol Chem . 2023 May; 404(7):645. PMID: 37232577
No abstract available.
8.
Bilsing F, Anlauf M, Hachani E, Khosa S, Schmitt L
Int J Mol Sci . 2023 Apr; 24(7). PMID: 37047196
Members of the superfamily of ABC transporters are found in all domains of life. Most of these primary active transporters act as isolated entities and export or import their substrates...
9.
Alhumaidi M, Nentwig L, Rahman H, Schmitt L, Rudrow A, Harris A, et al.
J Biol Chem . 2023 Apr; 299(4):104666. PMID: 37044027
No abstract available.
10.
Chacko F, Schmitt L
Biol Chem . 2023 Mar; 404(7):663-671. PMID: 36907826
epeats in oins (RTX) protein family is a group of exoproteins secreted by Type 1 secretion system (T1SS) of several Gram-negative bacteria. The term RTX is derived from the characteristic...