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Lutgarde Arckens

Explore the profile of Lutgarde Arckens including associated specialties, affiliations and a list of published articles. Areas
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Articles 121
Citations 1461
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Recent Articles
1.
Ayana R, Zandecki C, Van Houcke J, Marien V, Seuntjens E, Arckens L
Aging Cell . 2024 Jul; 23(10):e14251. PMID: 38949249
The African turquoise killifish (Nothobranchius furzeri) combines a short lifespan with spontaneous age-associated loss of neuro-regenerative capacity, an intriguing trait atypical for a teleost. The impact of aging on the...
2.
Kozak A, Ninghetto M, Wieteska M, Fiedorowicz M, Welniak-Kaminska M, Kossowski B, et al.
Behav Brain Funct . 2024 May; 20(1):13. PMID: 38789988
Background: Macular degeneration of the eye is a common cause of blindness and affects 8% of the worldwide human population. In adult cats with bilateral lesions of the central retina,...
3.
Marien V, Piskin I, Zandecki C, Van Houcke J, Arckens L
Front Behav Neurosci . 2024 Jan; 17:1326674. PMID: 38259633
The African turquoise killifish () has emerged as a popular model organism for neuroscience research in the last decade. One of the reasons for its popularity is its short lifespan...
4.
Pereira M, Ayana R, Holt M, Arckens L
Front Cell Dev Biol . 2023 Aug; 11:1193130. PMID: 37534103
Astrocytes are the major glial cell type in the central nervous system (CNS). Initially regarded as supportive cells, it is now recognized that this highly heterogeneous cell population is an...
5.
Van Houcke J, Marien V, Zandecki C, Ayana R, Pepermans E, Boonen K, et al.
NPJ Regen Med . 2023 Jun; 8(1):31. PMID: 37328477
The young African turquoise killifish has a high regenerative capacity, but loses it with advancing age, adopting several aspects of the limited form of mammalian regeneration. We deployed a proteomic...
6.
Marien V, Arckens L, Van Houcke J
Cold Spring Harb Protoc . 2023 Mar; 2024(2):107829. PMID: 36931736
Studying the brain at the single-cell level has become increasingly popular in recent years. This, however, remains challenging, especially in emerging model organisms. To carry out single-cell sequencing, the preparation...
7.
Marien V, Arckens L, Van Houcke J
Cold Spring Harb Protoc . 2023 Mar; 2024(2):107809. PMID: 36921997
The aging population (people >60 yr old) is steadily increasing worldwide, resulting in an increased prevalence of age-related neurodegenerative diseases. Despite intensive research efforts in the past decades, there are...
8.
Gilissen S, Hennes M, Arckens L
Methods Mol Biol . 2023 Mar; 2636:55-70. PMID: 36881295
Mapping immediate early gene (IEG) expression levels to characterize changes in neuronal activity patterns has become a golden standard in neuroscience research. Due to straightforward detection methods such as in...
9.
Verbruggen L, Ates G, Lara O, De Munck J, Villers A, De Pauw L, et al.
Mol Psychiatry . 2022 Feb; 27(4):2355-2368. PMID: 35181756
The cystine/glutamate antiporter system x has been identified as the major source of extracellular glutamate in several brain regions as well as a modulator of neuroinflammation, and genetic deletion of...
10.
Van Houcke J, Marien V, Zandecki C, Vanhunsel S, Moons L, Ayana R, et al.
Aging Cell . 2021 Aug; 20(9):e13464. PMID: 34428340
The aging central nervous system (CNS) of mammals displays progressive limited regenerative abilities. Recovery after loss of neurons is extremely restricted in the aged brain. Many research models fall short...