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Lushuang Xie

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Articles 19
Citations 195
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Recent Articles
1.
Liu H, You M, Yang H, Wu X, Zhang S, Huang S, et al.
Metab Brain Dis . 2025 Jan; 40(1):109. PMID: 39841296
The immune system has emerged as a major factor in the pathogenesis of Alzheimer's disease (AD). PANoptosis is a newly defined programmed cell death mechanism related to many inflammatory diseases....
2.
Liu H, Yi X, You M, Yang H, Zhang S, Huang S, et al.
Metab Brain Dis . 2024 Aug; 39(7):1469-1480. PMID: 39136807
Dysfunctional lactate metabolism in the brain has been implicated in neuroinflammation, Aβ deposition, and cell disturbance, all of which play a significant role in the pathogenesis of Alzheimer's disease (AD)....
3.
Xie L, Wu Q, Li K, Khan M, Zhang A, Sinha B, et al.
Aging Dis . 2024 Jun; 15(5):2168-2190. PMID: 38916729
Alzheimer's disease (AD) is an age-dependent neurodegenerative disease characterized by extracellular Amyloid Aβ peptide (Aβ) deposition and intracellular Tau protein aggregation. Glia, especially microglia and astrocytes are core participants during...
4.
Liu H, Yang H, Liu S, Li S, Yang W, Ayesha A, et al.
J Vis Exp . 2024 Jun; (207). PMID: 38829108
Many sex-specific biomarkers have been recently revealed in Alzheimer's disease (AD); however, cerebral glial cells were rarely reported. This study analyzed 220,095 single-nuclei transcriptomes from the frontal cortex of thirty-three...
5.
Liu H, Yang H, You M, Zhang S, Huang S, Tan X, et al.
J Mol Neurosci . 2024 May; 74(2):56. PMID: 38802701
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that presents a significant global health challenge. To explore drugs targeting key genes in AD, R software was used to analyze the...
6.
Liang B, Chen X, Li M, Zhang L, Yang X, Shi L, et al.
Pharm Biol . 2023 Dec; 62(1):42-52. PMID: 38112463
Context: Liuwei Dihuang pill (LWDH) has been used to treat postmenopausal osteoporosis (PMOP). Objective: To explore the effects and mechanisms of action of LWDH in PMOP. Materials And Methods: Forty-eight...
7.
Xie L, Rungratanawanich W, Yang Q, Tong G, Fu E, Lu S, et al.
Drug Discov Today . 2023 Mar; 28(5):103552. PMID: 36907319
The microbiota-gut-brain axis (MGBA) is important in maintaining the structure and function of the central nervous system (CNS) and is regulated by the CNS environment and signals from the peripheral...
8.
Liu S, Li H, Shen Y, Zhu W, Wang Y, Wang J, et al.
Front Aging Neurosci . 2023 Feb; 15:1069155. PMID: 36819717
Aquaporin-4 (AQP4) is highly polarized to perivascular astrocytic endfeet. Loss of AQP4 polarization is associated with many diseases. In Alzheimer's disease (AD), AQP4 loses its normal location and thus reduces...
9.
Zhang N, Shen Y, Zhu W, Li C, Liu S, Li H, et al.
Life Sci . 2022 Oct; 310:121052. PMID: 36220370
Aims: Alzheimer's disease (AD) is a common and irreversible neurodegenerative disease accompanied by extensive synaptic loss. Previous studies found that moxibustion had good therapeutic effects on AD. We here investigated...
10.
Jiang C, Li X, Liu C, Li G, Zheng Y, Xie L, et al.
Anat Rec (Hoboken) . 2022 Feb; 306(12):3085-3096. PMID: 35225421
Liver depression and spleen deficiency syndrome (LDSDS) and spleen-gastric damp-heat syndrome (SGDHS) are two major traditional Chinese medicine syndromes observed in chronic hepatitis B (CHB). Both syndromes exhibit significant differences...