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Luo Gu

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Articles 98
Citations 3431
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Recent Articles
1.
Amitrano A, Yuan Q, Agarwal B, Sen A, Dance Y, Zuo Y, et al.
Sci Adv . 2025 Jan; 11(1):eadr5023. PMID: 39742493
Human mesenchymal stem cells (hMSCs) respond to mechanical stimuli, including stiffness and viscoelasticity. To date, it is unknown how extracellular fluid viscosity affects hMSC function on substrates of different stiffness...
2.
Anantha P, Raj P, Saracino E, Kim J, Kim J, Convertino A, et al.
Adv Healthc Mater . 2024 Dec; 14(6):e2402960. PMID: 39740118
Astrocytes, integral components of the central nervous system, are increasingly recognized for their multifaceted roles beyond support cells. Despite their acknowledged importance, understanding the intricacies of astrocyte morphological dynamics remains...
3.
Wu Y, Song Y, Soto J, Hoffman T, Zhang A, Han X, et al.
bioRxiv . 2024 Apr; PMID: 38659850
Living tissue and extracellular matrices possess viscoelastic properties, but understanding how viscoelastic matrix regulates chromatin and the epigenome is limited. Here, we find that the regulation of the epigenetic state...
4.
Sneider A, Liu Y, Starich B, Du W, Nair P, Marar C, et al.
Cancer Res Commun . 2024 Apr; 4(5):1240-1252. PMID: 38630893
Significance: Here we show that the quantity, cargo, and function of breast cancer-derived EVs vary with mechanical properties of the extracellular microenvironment.
5.
Raj P, Wu L, Arora S, Bhatt R, Zuo Y, Fang Z, et al.
Sens Actuators B Chem . 2024 Mar; 404. PMID: 38524639
Recent advances in Raman spectroscopy have shown great potential for non-invasive analyte sensing, but the lack of a standardized optical phantom for these measurements has hindered further progress. While many...
6.
Marino-Bravante G, Carey A, Huser L, Dixit A, Wang V, Kaur A, et al.
Nat Aging . 2024 Mar; 4(3):350-363. PMID: 38472454
Melanoma, the most lethal form of skin cancer, often has worse outcomes in older patients. We previously demonstrated that an age-related decrease in the secreted extracellular matrix (ECM) protein HAPLN1...
7.
Starich B, Yang F, Tanrioven D, Kung H, Baek J, Nair P, et al.
bioRxiv . 2024 Feb; PMID: 38370721
Cellular senescence is a major driver of aging and disease. Here we show that substrate stiffness modulates the emergence and magnitude of senescence phenotypes after exposure to senescence inducers. Using...
8.
Li X, Zhao X, Zhang L, Mathur A, Xu Y, Fang Z, et al.
Nat Commun . 2024 Feb; 15(1):1175. PMID: 38331931
Efficient CO separation technologies are essential for mitigating climate change. Compared to traditional thermochemical methods, electrochemically mediated carbon capture using redox-tunable sorbents emerges as a promising alternative due to its...
9.
Tran A, Wisniewski E, Mistriotis P, Stoletov K, Parlani M, Amitrano A, et al.
Res Sq . 2024 Jan; PMID: 38260442
Cells migrating in confinement experience mechanical challenges whose consequences on cell migration machinery remain only partially understood. Here, we demonstrate that a pool of the cytokinesis regulatory protein anillin is...
10.
Kim J, Iyer S, Tessman C, Lakshman S, Kang H, Gu L
bioRxiv . 2023 Oct; PMID: 37904934
Calcium ion-crosslinked alginate hydrogels are widely used as a materials system for investigating cell behavior in 3D environments . Suspensions of calcium sulfate particles are often used as the source...