Luke P Allsopp
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Explore the profile of Luke P Allsopp including associated specialties, affiliations and a list of published articles.
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26
Citations
905
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Recent Articles
1.
Habich A, Chaves Vargas V, Robinson L, Allsopp L, Unterweger D
Nat Commun
. 2025 Jan;
16(1):888.
PMID: 39837841
Bacterial type VI secretion systems (T6SSs) are puncturing molecular machines that transport effector proteins to kill microbes, manipulate eukaryotic cells, or facilitate nutrient uptake. How and why T6SS machines and...
2.
Gahlot D, Patkowski J, Fernandez de Santaella J, Allsopp L, Pan Z, Filloux A, et al.
NPJ Antimicrob Resist
. 2024 Nov;
2(1):39.
PMID: 39568730
Antibiotic resistance is a global healthcare crisis. Bacteria are highly adaptable and can rapidly acquire mechanisms of resistance towards conventional antibiotics. The permeability barrier conferred by the Gram-negative bacteria cell...
3.
Ellis H, Allsopp L
Am J Respir Cell Mol Biol
. 2024 Jul;
71(6):625-627.
PMID: 39051864
No abstract available.
4.
Phan M, Schirra H, Nhu N, Peters K, Sarkar S, Allsopp L, et al.
mBio
. 2024 Feb;
15(3):e0338823.
PMID: 38353545
Importance: Uropathogenic (UPEC) cause ~80% of all urinary tract infections (UTIs), with increasing rates of antibiotic resistance presenting an urgent threat to effective treatment. To cause infection, UPEC must grow...
5.
Allsopp L, Bernal P
Microbiology (Reading)
. 2023 Jul;
169(7).
PMID: 37490402
The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to optimize their environment, including deploying the type VI secretion system (T6SS). Acting as a bacterial...
6.
Robinson L, Collins A, Murphy R, Davies J, Allsopp L
Front Microbiol
. 2023 Jan;
13:1042505.
PMID: 36687572
is an opportunistic pathogen and a major driver of morbidity and mortality in people with Cystic Fibrosis (CF). The Type VI secretion system (T6SS) is a molecular nanomachine that translocates...
7.
Nolan L, Allsopp L
Adv Exp Med Biol
. 2022 Oct;
1386:223-256.
PMID: 36258074
Pseudomonas aeruginosa is a robust and versatile organism capable of surviving and prospering in a diverse array of environments and is an opportunistic pathogen of humans. One reason for the...
8.
Demmer J, Phillips B, Uhrig O, Filloux A, Allsopp L, Bublitz M, et al.
Sci Adv
. 2022 Feb;
8(7):eabl5966.
PMID: 35171679
The global spread of multidrug-resistant infections urgently calls for the identification of novel drug targets. We solved the electron cryo-microscopy structure of the FF-adenosine 5'-triphosphate (ATP) synthase from in three...
9.
Alvarez-Fraga L, Phan M, Goh K, Nhu N, Hancock S, Allsopp L, et al.
mBio
. 2022 Jan;
13(1):e0351921.
PMID: 35038925
Many antibiotic resistant uropathogenic Escherichia coli (UPEC) strains belong to clones defined by their multilocus sequence type (ST), with ST131 being the most dominant. Although we have a good understanding...
10.
Allsopp L, Collins A, Hawkins E, Wood T, Filloux A
Nucleic Acids Res
. 2021 Dec;
50(1):227-243.
PMID: 34928327
Pseudomonas aeruginosa uses three type six secretion systems (H1-, H2- and H3-T6SS) to manipulate its environment, subvert host cells and for microbial competition. These T6SS machines are loaded with a...