Luke D Amer
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Explore the profile of Luke D Amer including associated specialties, affiliations and a list of published articles.
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8
Citations
184
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Recent Articles
1.
Saleh L, Amer L, Thompson B, Danhorn T, Knapp J, Gibbings S, et al.
Adv Healthc Mater
. 2021 Dec;
11(9):e2102209.
PMID: 34967497
Poly(ethylene glycol) (PEG) hydrogels hold promise for in vivo applications but induce a foreign body response (FBR). While macrophages are key in the FBR, many questions remain. This study investigates...
2.
Amer L, Saleh L, Walker C, Thomas S, Janssen W, Alper S, et al.
Acta Biomater
. 2019 Oct;
100:105-117.
PMID: 31568879
Synthetic hydrogels, such as poly(ethylene glycol) (PEG), are promising for a range of in vivo applications. However, like all non-biological biomaterials, synthetic hydrogels including PEG elicit a foreign body response...
3.
Jansen L, Amer L, Chen E, Nguyen T, Saleh L, Emrick T, et al.
Biomacromolecules
. 2018 Apr;
19(7):2880-2888.
PMID: 29698603
Reducing the foreign body response (FBR) to implanted biomaterials will enhance their performance in tissue engineering. Poly(ethylene glycol) (PEG) hydrogels are increasingly popular for this application due to their low...
4.
Amer L, Bryant S
Ann Biomed Eng
. 2016 Apr;
44(6):1959-69.
PMID: 27080375
Enzyme-sensitive hydrogels are a promising class of materials for cell encapsulation and tissue engineering because their ability to be degraded by cell-secreted factors. However, it is well known that nearly...
5.
Amer L, Holtzinger A, Keller G, Mahoney M, Bryant S
Acta Biomater
. 2015 Apr;
22:103-10.
PMID: 25913222
This study aimed to develop a three dimensional culture platform for aggregates of human embryonic stem cell (hESC)-derived pancreatic progenitors that enables long-term culture, maintains aggregate size and morphology, does...
6.
Swartzlander M, Blakney A, Amer L, Hankenson K, Kyriakides T, Bryant S
Biomaterials
. 2014 Dec;
41:79-88.
PMID: 25522967
The implantation of non-biological materials, including scaffolds for tissue engineering, ubiquitously leads to a foreign body response (FBR). We recently reported that this response negatively impacts fibroblasts encapsulated within a...
7.
Amer L, Mahoney M, Bryant S
Tissue Eng Part B Rev
. 2014 Jan;
20(5):455-67.
PMID: 24417705
Type 1 diabetes mellitus is an autoimmune disease resulting from the destruction of insulin-producing pancreatic β-cells. Cell-based therapies, involving the transplantation of functional β-cells into diabetic patients, have been explored...
8.
Soderquist R, Sloane E, Loram L, Harrison J, Dengler E, Johnson S, et al.
Pharm Res
. 2010 Mar;
27(5):841-54.
PMID: 20224990
Purpose: Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from...