Luke Becker
Overview
Explore the profile of Luke Becker including associated specialties, affiliations and a list of published articles.
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29
Citations
530
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Recent Articles
1.
Wong Y, Rosa B, Becker L, Camberis M, LeGros G, Zhan B, et al.
PLoS Negl Trop Dis
. 2025 Jan;
19(1):e0012780.
PMID: 39832284
More than 470 million people globally are infected with the hookworms Ancylostoma ceylanicum and Necator americanus, resulting in an annual loss of 2.1 to 4 million disability-adjusted-life-years. Current infection management...
2.
Lennox-Bulow D, Becker L, Loukas A, Seymour J, Smout M
Front Parasitol
. 2025 Jan;
2():1189872.
PMID: 39816842
Parasitic worms (helminths) infect almost all taxa across the animal kingdom, and pose significant challenges to public health and economies, particularly in developing countries. To address this problem, researchers have...
3.
Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes
Pierce D, McDonald M, Merone L, Becker L, Thompson F, Lewis C, et al.
Nat Commun
. 2023 Jul;
14(1):4503.
PMID: 37495576
The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic parasitic worm infections suggests a protective role for worms against metabolic disorders, however clinical evidence has...
4.
Dickson B, Masson J, Mayfield H, Aye K, Htwe K, Roineau M, et al.
Trop Med Infect Dis
. 2022 Jul;
7(7).
PMID: 35878125
The elimination of lymphatic filariasis (LF) is achieved through repeated mass drug administration (MDA) of anti-filarial medications, which interrupts transmission and prevents new infections. Accurate transmission assessments are critical to...
5.
Chapman P, Llewellyn S, Jennings H, Becker L, Giacomin P, McDougall R, et al.
Parasit Vectors
. 2022 Jul;
15(1):242.
PMID: 35804460
Background: Although there is unprecedented interest in experimental human hookworm infection, details of hookworm manufacture and characterisation have been sparsely reported. In this report, we detail the production and characterisation...
6.
Shalash A, Becker L, Yang J, Giacomin P, Pearson M, Hussein W, et al.
J Allergy Clin Immunol
. 2022 Mar;
150(1):157-169.e10.
PMID: 35278494
Background: Approximately 400 million individuals are infected with hookworms globally. Protective vaccines are needed to prevent reinfections, which often occur after drug treatment in endemic areas. Ideal vaccines are highly...
7.
Mekonnen G, Tedla B, Pearson M, Becker L, Field M, Amoah A, et al.
PLoS Negl Trop Dis
. 2022 Jan;
16(1):e0010151.
PMID: 35073344
Schistosoma haematobium is the leading cause of urogenital schistosomiasis and it is recognised as a class 1 carcinogen due to the robust association of infection with bladder cancer. In schistosomes,...
8.
Pearson M, Tedla B, Mekonnen G, Proietti C, Becker L, Nakajima R, et al.
Lancet Microbe
. 2022 Jan;
2(11):e617-e626.
PMID: 34977830
Background: Sensitive diagnostics are needed for effective management and surveillance of schistosomiasis so that current transmission interruption goals set by WHO can be achieved. We aimed to screen the secretome...
9.
Shalash A, Becker L, Yang J, Giacomin P, Pearson M, Hussein W, et al.
Vaccines (Basel)
. 2021 Sep;
9(9).
PMID: 34579271
Approximately 0.4 billion individuals worldwide are infected with hookworm. An effective vaccine is needed to not only improve the health of those affected and at high risk, but also to...
10.
Chapman P, Webster R, Giacomin P, Llewellyn S, Becker L, Pearson M, et al.
Lancet Infect Dis
. 2021 Aug;
21(12):1725-1736.
PMID: 34419209
Background: Control of human hookworm infection would be greatly aided by the development of an effective vaccine. We aimed to develop a live attenuated human hookworm vaccine. Methods: This was...