Lukasz P Slomnicki
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Explore the profile of Lukasz P Slomnicki including associated specialties, affiliations and a list of published articles.
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18
Citations
376
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Recent Articles
1.
Gao Y, Slomnicki L, Kilanczyk E, Forston M, Pietrzak M, Rouchka E, et al.
ASN Neuro
. 2024 Jul;
16(1):2371162.
PMID: 39024571
Endoplasmic reticulum (ER) stress in oligodendrocyte (OL) linage cells contributes to several CNS pathologies including traumatic spinal cord injury (SCI) and multiple sclerosis. Therefore, primary rat OL precursor cell (OPC)...
2.
Gao Y, Wei G, Forston M, Rood B, Hodges E, Burke D, et al.
Sci Rep
. 2023 Jun;
13(1):9193.
PMID: 37280306
The integrated stress response (ISR)-activated transcription factors ATF4 and CHOP/DDIT3 may regulate oligodendrocyte (OL) survival, tissue damage and functional impairment/recovery in white matter pathologies, including traumatic spinal cord injury (SCI)....
3.
Hetman M, Slomnicki L, Hodges E, Saraswat Ohri S, Whittemore S
Exp Neurol
. 2022 Apr;
353:114080.
PMID: 35405120
A wide range of physiological processes show circadian oscillations that are critical for organismal homeostasis. Consequently, disruption of such rhythmicity contributes to the pathogenesis of various chronic diseases. The occurrence,...
4.
Slomnicki L, Wei G, Burke D, Hodges E, Myers S, Yarberry C, et al.
PLoS One
. 2021 Nov;
16(11):e0249981.
PMID: 34813603
The circadian gene expression rhythmicity drives diurnal oscillations of physiological processes that may determine the injury response. While outcomes of various acute injuries are affected by the time of day...
5.
Slomnicki L, Myers S, Saraswat Ohri S, Parsh M, Andres K, Chariker J, et al.
Sci Rep
. 2020 Aug;
10(1):14212.
PMID: 32848194
The transcription factor BMAL1/ARNTL is a non-redundant component of the clock pathway that regulates circadian oscillations of gene expression. Loss of BMAL1 perturbs organismal homeostasis and usually exacerbates pathological responses...
6.
Hetman M, Slomnicki L
J Neurochem
. 2018 Aug;
148(3):325-347.
PMID: 30144322
Development of the nervous system is carried out by complex gene expression programs that are regulated at both transcriptional and translational level. In addition, quality control mechanisms such as the...
7.
Vashishta A, Slomnicki L, Pietrzak M, Smith S, Kolikonda M, Naik S, et al.
Mol Neurobiol
. 2018 Mar;
55(11):8374-8387.
PMID: 29546592
Ribosome biogenesis, including the RNA polymerase 1 (Pol1)-mediated transcription of rRNA, is regulated by the pro-epileptogenic mTOR pathway. Therefore, hippocampal Pol1 activity was examined in mouse models of epilepsy including...
8.
Slomnicki L, Chung D, Parker A, Hermann T, Boyd N, Hetman M
Sci Rep
. 2017 Dec;
7(1):16652.
PMID: 29192272
We report here that in rat and human neuroprogenitor cells as well as rat embryonic cortical neurons Zika virus (ZIKV) infection leads to ribosomal stress that is characterized by structural...
9.
Slomnicki L, Hallgren J, Vashishta A, Smith S, Ellis S, Hetman M
Mol Neurobiol
. 2016 Dec;
55(1):538-553.
PMID: 27975169
While impaired ribosomal biogenesis is observed in neurodegenerative diseases, its pathogenic contributions are not clear. For instance, it is well established that in rodent neurons, genetic inhibition of RNA-polymerase 1...
10.
Slomnicki L, Malinowska A, Kistowski M, Palusinski A, Zheng J, Sepp M, et al.
Mol Cell Proteomics
. 2016 Apr;
15(6):2055-75.
PMID: 27053602
To study nucleolar involvement in brain development, the nuclear and nucleolar proteomes from the rat cerebral cortex at postnatal day 7 were analyzed using LC-MS/iTRAQ methodology. Data of the analysis...