Lukasz Jaroszewski
Overview
Explore the profile of Lukasz Jaroszewski including associated specialties, affiliations and a list of published articles.
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Articles
173
Citations
3722
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Recent Articles
1.
Patel D, Stogios P, Jaroszewski L, Urbanus M, Sedova M, Semper C, et al.
Mol Syst Biol
. 2024 Nov;
21(1):59-89.
PMID: 39562741
Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds of effector proteins inside eukaryotic cells to ensure intracellular replication. Our understanding of the molecular functions of the...
2.
Qiu X, Nair M, Jaroszewski L, Godzik A
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892129
This study focuses on understanding the transcriptional heterogeneity of activated platelets and its impact on diseases such as sepsis, COVID-19, and systemic lupus erythematosus (SLE). Recognizing the limited knowledge in...
3.
Vendel A, Jaroszewski L, Linnik M, Godzik A
Clin Pharmacol Ther
. 2024 Apr;
116(1):247-256.
PMID: 38676311
B- and T-lymphocyte attenuator (BTLA; CD272) is an immunoglobulin superfamily member and part of a family of checkpoint inhibitory receptors that negatively regulate immune cell activation. The natural ligand for...
4.
Takkouche A, Qiu X, Sedova M, Jaroszewski L, Godzik A
J Struct Biol
. 2023 Aug;
215(3):108011.
PMID: 37562586
Leucine Rich Repeat (LRR) domains, are present in hundreds of thousands of proteins across all kingdoms of life and are typically involved in protein-protein interactions and ligand recognition. LRR domains...
5.
Turner S, Alisoltani A, Bratt D, Cohen-Lavi L, Dearlove B, Drosten C, et al.
Emerg Infect Dis
. 2023 Apr;
29(5).
PMID: 37054986
Since late 2020, SARS-CoV-2 variants have regularly emerged with competitive and phenotypic differences from previously circulating strains, sometimes with the potential to escape from immunity produced by prior exposure and...
6.
Alisoltani A, Qiu X, Jaroszewski L, Sedova M, Iyer M, Godzik A
Arch Biochem Biophys
. 2023 Mar;
739:109579.
PMID: 36933758
Both gender and smoking are correlated with prevalence and outcomes in many types of cancers. Tobacco smoke is a known carcinogen through its genotoxicity but can also affect cancer progression...
7.
Alisoltani A, Jaroszewski L, Godzik A, Iranzadeh A, Simons L, Dean T, et al.
Viruses
. 2022 Dec;
14(12).
PMID: 36560718
The unprecedented growth of publicly available SARS-CoV-2 genome sequence data has increased the demand for effective and accessible SARS-CoV-2 data analysis and visualization tools. The majority of the currently available...
8.
Bonenfant J, Li J, Nasouf L, Miller J, Lowe T, Jaroszewski L, et al.
J Inflamm Res
. 2022 Jul;
15:3925-3940.
PMID: 35860230
Background: Sepsis mortality has remained unchanged for greater than a decade, and early recognition continues to be the most important factor in mortality outcome. Plasma resistin concentration is increased in...
9.
Iyer M, Jaroszewski L, Sedova M, Godzik A
Protein Sci
. 2022 Jun;
31(7):e4325.
PMID: 35762711
Proteins sample a multitude of different conformations by undergoing small- and large-scale conformational changes that are often intrinsic to their functions. Information about these changes is often captured in the...
10.
Alisoltani A, Jaroszewski L, Iyer M, Iranzadeh A, Godzik A
Front Genet
. 2022 Jun;
13:875406.
PMID: 35719386
Most attention in the surveillance of evolving SARS-CoV-2 genome has been centered on nucleotide substitutions in the spike glycoprotein. We show that, as the pandemic extends into its second year,...