Luisa Speranza
Overview
Explore the profile of Luisa Speranza including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
552
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Recent Articles
1.
Speranza L, Miniaci M, Volpicelli F
Biomedicines
. 2025 Feb;
13(2).
PMID: 40002905
Dopamine, a key neurotransmitter in the central nervous system, is essential for regulating a wide range of physiological processes, including motor control, reward processing, mood regulation, and decision-making [...].
2.
Speranza L, Filiz K, Lippiello P, Ferraro M, Pascarella S, Miniaci M, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335492
Stress profoundly affects physical and mental health, particularly when experienced early in life. Early-life stress (ELS) encompasses adverse childhood experiences such as abuse, neglect, violence, or chronic poverty. These stressors...
3.
Speranza L, Molinari M, Volpicelli F, Lacivita E, Leopoldo M, Pulcrano S, et al.
Brain Res
. 2024 Feb;
1830:148815.
PMID: 38387714
Antipsychotic drugs (APDs) are the primary pharmacological treatment for schizophrenia, a complex disorder characterized by altered neuronal connectivity. Atypical or second-generation antipsychotics, such as Risperidone (RSP) and Clozapine (CZP) predominantly...
4.
Pulcrano S, De Gregorio R, De Sanctis C, Volpicelli F, Piscitelli R, Speranza L, et al.
J Neurosci
. 2023 Oct;
43(48):8104-8125.
PMID: 37816598
In the brain, microRNAs (miRNAs) are believed to play a role in orchestrating synaptic plasticity at a higher level by acting as an additional mechanism of translational regulation, alongside the...
5.
Speranza L, Filiz K, Goebel S, Perrone-Capano C, Pulcrano S, Volpicelli F, et al.
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359212
Structural, functional, and molecular alterations in excitatory spines are a common hallmark of many neurodevelopmental disorders including intellectual disability and autism. Here, we describe an optimized methodology, based on combined...
6.
De Gregorio R, Subah G, Chan J, Speranza L, Zhang X, Ramakrishnan A, et al.
Development
. 2022 Sep;
149(21).
PMID: 36178075
Neurodevelopmental disorders ranging from autism to intellectual disability display sex-biased prevalence and phenotypical presentations. Despite increasing knowledge about temporospatial cortical map development and genetic variants linked to neurodevelopmental disorders, when...
7.
Speranza L, Pulcrano S, Perrone-Capano C, di Porzio U, Volpicelli F
Rev Neurosci
. 2022 Mar;
33(7):789-801.
PMID: 35325516
In a million years, under the pressure of natural selection, hominins have acquired the abilities for vocal learning, music, and language. Music is a relevant human activity, highly effective in...
8.
Speranza L, Inglebert Y, De Sanctis C, Wu P, Kalinowska M, McKinney R, et al.
J Neurosci
. 2022 Jan;
42(9):1666-1678.
PMID: 35046120
Dendritic spines, actin-rich protrusions forming the postsynaptic sites of excitatory synapses, undergo activity-dependent molecular and structural remodeling. Activation of Group 1 metabotropic glutamate receptors (mGluR1 and mGluR5) by synaptic or...
9.
Speranza L, di Porzio U, Viggiano D, de Donato A, Volpicelli F
Cells
. 2021 Apr;
10(4).
PMID: 33810328
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions including motor control, modulation of affective and emotional states, reward mechanisms, reinforcement of behavior, and selected higher cognitive functions....
10.
Colucci-DAmato L, Speranza L, Volpicelli F
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33096634
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin receptor kinase B (TrkB) and the low...