Luis Perez de Sevilla Muller
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Explore the profile of Luis Perez de Sevilla Muller including associated specialties, affiliations and a list of published articles.
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20
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791
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Recent Articles
1.
Matynia A, Recio B, Myers Z, Parikh S, Goit R, Brecha N, et al.
Invest Ophthalmol Vis Sci
. 2024 Jan;
65(1):28.
PMID: 38224335
Purpose: Intrinsically photosensitive retinal ganglion cells (ipRGCs) play a crucial role in non-image-forming visual functions. Given their significant loss observed in various ocular degenerative diseases at early stages, this study...
2.
Chen A, Azar S, Harris A, Brecha N, Perez de Sevilla Muller L
Front Neuroanat
. 2021 Jun;
15:629244.
PMID: 34093139
Manipulation of the phosphatase and tensin homolog (PTEN) pathway has been suggested as a therapeutic approach to treat or prevent vision loss due to retinal disease. In this study, we...
3.
Perez de Sevilla Muller L, Azar S, de Los Santos J, Brecha N
Front Neuroanat
. 2017 May;
11:39.
PMID: 28529477
The transcription factor Prox1 is expressed in multiple cells in the retina during eye development. This study has focused on neuronal Prox1 expression in the inner nuclear layer (INL) of...
4.
Perez de Sevilla Muller L, Solomon A, Sheets K, Hapukino H, Rodriguez A, Brecha N
J Comp Neurol
. 2017 May;
527(1):133-158.
PMID: 28472856
Amacrine cells are a heterogeneous group of interneurons that form microcircuits with bipolar, amacrine and ganglion cells to process visual information in the inner retina. This study has characterized the...
5.
Matynia A, Nguyen E, Sun X, Blixt F, Parikh S, Kessler J, et al.
Front Neural Circuits
. 2016 Aug;
10:60.
PMID: 27559310
The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing...
6.
Hirano A, Liu X, Boulter J, Grove J, Perez de Sevilla Muller L, Barnes S, et al.
eNeuro
. 2016 Mar;
3(2).
PMID: 27022629
The cellular mechanisms underlying feedback signaling from horizontal cells to photoreceptors, which are important for the formation of receptive field surrounds of early visual neurons, remain unsettled. Mammalian horizontal cells...
7.
Perez de Sevilla Muller L, Sargoy A, Fernandez-Sanchez L, Rodriguez A, Liu J, Cuenca N, et al.
J Comp Neurol
. 2015 Jan;
523(10):1443-60.
PMID: 25631988
High-voltage-activated calcium channels are hetero-oligomeric protein complexes that mediate multiple cellular processes, including the influx of extracellular Ca(2+), neurotransmitter release, gene transcription, and synaptic plasticity. These channels consist of a...
8.
Sargoy A, Barnes S, Brecha N, Perez de Sevilla Muller L
J Vis Exp
. 2014 Oct;
(92):e51396.
PMID: 25349920
In this paper we describe the tools, reagents, and the practical steps that are needed for: 1) successful preparation of wholemount retinas for immunohistochemistry and, 2) calcium imaging for the...
9.
Fernandez-Sanchez L, Perez de Sevilla Muller L, Brecha N, Cuenca N
Invest Ophthalmol Vis Sci
. 2014 Aug;
55(9):6059-72.
PMID: 25118265
Purpose: The DBA/2J mouse line develops essential iris atrophy, pigment dispersion, and glaucomatous age-related changes, including an increase of IOP, optic nerve atrophy, and retinal ganglion cell (RGC) death. The...
10.
Perez de Sevilla Muller L, Sargoy A, Rodriguez A, Brecha N
PLoS One
. 2014 Mar;
9(3):e93274.
PMID: 24671191
We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically...