Luis Pereira de Almeida
Overview
Explore the profile of Luis Pereira de Almeida including associated specialties, affiliations and a list of published articles.
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127
Citations
3909
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Recent Articles
11.
Carvalho S, Santos J, Moreira L, Duarte A, Gaspar P, Rocha H, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542525
Among the many lysosomal storage disorders (LSDs) that would benefit from the establishment of novel cell models, either patient-derived or genetically engineered, is mucopolysaccharidosis type II (MPS II). Here, we...
12.
Raposo M, Hubener-Schmid J, Tagett R, Ferreira A, Melo A, Vasconcelos J, et al.
Neurobiol Dis
. 2024 Feb;
193:106456.
PMID: 38423193
Spinocerebellar ataxia type 3 (SCA3)/Machado-Joseph disease (MJD) is a heritable proteinopathy disorder, whose causative gene, ATXN3, undergoes alternative splicing. Ataxin-3 protein isoforms differ in their toxicity, suggesting that certain ATXN3...
13.
Soares Martins T, Pelech S, Ferreira M, Pinho B, Leandro K, de Almeida L, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338863
Phosphorylation plays a key role in Alzheimer's disease (AD) pathogenesis, impacting distinct processes such as amyloid-beta (Aβ) peptide production and tau phosphorylation. Impaired phosphorylation events contribute to senile plaques and...
14.
Mendonca L, Henriques D, Fernandes V, Moreira R, Bras J, Duarte S, et al.
Sci Rep
. 2024 Feb;
14(1):3236.
PMID: 38332227
Machado-Joseph disease (MJD) is a neurodegenerative disorder characterized by widespread neuronal death affecting the cerebellum. Cell therapy can trigger neuronal replacement and neuroprotection through bystander effects providing a therapeutic option...
15.
Henriques C, Lopes M, Silva A, Lobo D, Badin R, Hantraye P, et al.
Brain
. 2024 Jan;
147(4):1166-1189.
PMID: 38284949
Polyglutamine disorders are a complex group of incurable neurodegenerative disorders caused by an abnormal expansion in the trinucleotide cytosine-adenine-guanine tract of the affected gene. To better understand these disorders, our...
16.
Lopes-Nunes J, Simoes P, Moreira D, Leandro K, Nobre R, de Almeida L, et al.
Int J Biol Macromol
. 2024 Jan;
259(Pt 2):129157.
PMID: 38199539
Oral cancer incidence and mortality are increasing over time. The most common therapies for oral cancers are surgery and radiotherapy, either used alone or combined, and immunotherapy can be also...
17.
Hengel H, Martus P, Faber J, Giunti P, Garcia-Moreno H, Solanky N, et al.
J Neurol
. 2023 Nov;
271(1):628-629.
PMID: 37979094
No abstract available.
18.
Faber J, Berger M, Wilke C, Hubener-Schmid J, Schaprian T, Santana M, et al.
Ann Neurol
. 2023 Nov;
95(2):400-406.
PMID: 37962377
Spinocerebellar ataxia type 3/Machado-Joseph disease is the most common autosomal dominant ataxia. In view of the development of targeted therapies, knowledge of early biomarker changes is needed. We analyzed cross-sectional...
19.
Ferreira-Marques M, Carvalho A, Franco A, Leal A, Botelho M, Carmo-Silva S, et al.
Aging Cell
. 2023 Oct;
22(12):e13983.
PMID: 37858983
Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal genetic condition that arises from a single nucleotide alteration in the LMNA gene, leading to the production of a defective lamin...
20.
Arnaut Z, Pinto S, Aroso R, Amorim A, Lobo C, Schaberle F, et al.
Photochem Photobiol Sci
. 2023 Sep;
22(11):2607-2620.
PMID: 37755667
The COVID-19 pandemic exposes our vulnerability to viruses that acquire the ability to infect our cells. Classical disinfection methods are limited by toxicity. Existing medicines performed poorly against SARS-CoV-2 because...