Luis P Fonseca
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Explore the profile of Luis P Fonseca including associated specialties, affiliations and a list of published articles.
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32
Citations
282
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Recent Articles
1.
de Barros D, Fonseca L, Goncalves L, Serrano D, Oliva A
Pharmaceutics
. 2024 Jun;
16(6).
PMID: 38931876
Biodegradable aliphatic polyester formulations as carriers for topical drug delivery show the potential to encapsulate structurally different therapeutic compounds. Poly(octamethylene suberate) (POS) nanoparticles (POS-NPs) were used as a matrix to...
2.
Fonseca L, Taipa M
Biomimetics (Basel)
. 2024 Jan;
9(1).
PMID: 38275454
Cutinase from is an enzyme that bridges functional properties between lipases and esterases, with applications in detergents, food processing, and the synthesis of fine chemicals. The purification procedure of recombinant...
3.
de Barros D, Santos R, Reed P, Fonseca L, Oliva A
Molecules
. 2022 Dec;
27(24).
PMID: 36557947
The biological activity of natural plant-oil-based nanostructured lipid carriers (NPO-NLCs) can be enhanced by the encapsulation of bioactive compounds, and they in turn can improve topical delivery of the drugs....
4.
Oliveira S, Sarmento E, Marinho V, Pereira R, Fonseca L, Ferreira I
Molecules
. 2022 Aug;
27(16).
PMID: 36014427
This work developd nanomaterials formulated from annatto seed oily extract (ASE), myristic acid (tetradecanoic acid), and their fatty acid esters. The annatto seed oily extract was obtained using only soybean...
5.
Pinto F, Fonseca L, de Barros D
Adv Exp Med Biol
. 2022 May;
1357:83-114.
PMID: 35583641
During the recent decades, dermal delivery has achieved visible popularity mainly due to the increase of chronic skin diseases and the demand for targeted delivery and patient compliance. Dermal delivery...
6.
Esgueira V, Lopes C, Dos Santos A, Pinto F, Sousa S, de Barros D, et al.
Adv Exp Med Biol
. 2022 May;
1357:43-82.
PMID: 35583640
The extensive knowledge in the miniemulsion technique used in biocatalysis applications by the authors allowed the development of drug delivery systems that constitutes the LipNanoCar technology core for the production...
7.
Ramanaiah S, Cordas C, Matias S, Reddy M, Leitao J, Fonseca L
Biotechnol Rep (Amst)
. 2021 Dec;
32:e00693.
PMID: 34917493
In the present work, power generation and substrate removal efficiencies of long-term operated microbial fuel cells, containing abiotic cathodes and biocathodes, were evaluated for 220 days. Among the two microbial...
8.
da Cunha B, Aleixo S, Fonseca L, Calado C
Biotechnol Bioeng
. 2021 Aug;
118(11):4465-4476.
PMID: 34396508
Structural modifications of known antibiotic scaffolds have kept the upper hand on resistance, but we are on the verge of not having antibiotics for many common infections. Mechanism-based discovery assays...
9.
da Cunha B, Zoio P, Fonseca L, Calado C
Antibiotics (Basel)
. 2021 Jun;
10(5).
PMID: 34065815
There are two main strategies for antibiotic discovery: target-based and phenotypic screening. The latter has been much more successful in delivering first-in-class antibiotics, despite the major bottleneck of delayed Mechanism-of-Action...
10.
da Cunha B, Fonseca L, Calado C
Appl Microbiol Biotechnol
. 2021 Jan;
105(3):1269-1286.
PMID: 33443637
The low rate of discovery and rapid spread of resistant pathogens have made antibiotic discovery a worldwide priority. In cell-based screening, the mechanism of action (MOA) is identified after antimicrobial...