Luis Martinez-Lostao
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Explore the profile of Luis Martinez-Lostao including associated specialties, affiliations and a list of published articles.
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60
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1311
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Recent Articles
21.
Sesma A, Pardo J, Cruellas M, M Galvez E, Gascon M, Isla D, et al.
Cancers (Basel)
. 2020 Oct;
12(10).
PMID: 33066479
Despite therapeutic advances, lung cancer (LC) is one of the leading causes of cancer morbidity and mortality worldwide. Recently, the treatment of advanced LC has experienced important changes in survival...
22.
Pinol R, Zeler J, Brites C, Gu Y, Tellez P, Carneiro Neto A, et al.
Nano Lett
. 2020 Aug;
20(9):6466-6472.
PMID: 32787172
Measurement of thermogenesis in individual cells is a remarkable challenge due to the complexity of the biochemical environment (such as pH and ionic strength) and to the rapid and yet...
23.
Garzon-Tituana M, Arias M, Sierra-Monzon J, Morte-Romea E, Santiago L, Ramirez-Labrada A, et al.
Front Immunol
. 2020 Jul;
11:1054.
PMID: 32655547
Sepsis is a serious global health problem. In addition to a high incidence, this syndrome has a high mortality and is responsible for huge health expenditure. The pathophysiology of sepsis...
24.
Santiago L, Castro M, Sanz-Pamplona R, Garzon M, Ramirez-Labrada A, Tapia E, et al.
Cell Rep
. 2020 Jul;
32(1):107847.
PMID: 32640217
If not properly regulated, the inflammatory immune response can promote carcinogenesis, as evident in colorectal cancer (CRC). Aiming to gain mechanistic insight into the link between inflammation and CRC, we...
25.
Gascon M, Isla D, Cruellas M, M Galvez E, Lastra R, Ocariz M, et al.
Cells
. 2020 Jun;
9(6).
PMID: 32580514
The molecular and cell determinants that modulate immune checkpoint (ICI) efficacy in lung cancer are still not well understood. However, there is a necessity to select those patients that will...
26.
de Miguel D, Gallego-Lleyda A, Martinez-Ara M, Plou J, Anel A, Martinez-Lostao L
Cancers (Basel)
. 2019 Dec;
11(12).
PMID: 31817469
Although TRAIL (TNF-related apoptosis-inducing ligand, also known as Apo2L) was described as capable of inducing apoptosis in transformed cells while sparing normal cells, limited results obtained in clinical trials has...
27.
Ibanez-Perez R, Guerrero-Ochoa P, Al-Wasaby S, Navarro R, Tapia-Galisteo A, de Miguel D, et al.
Oncoimmunology
. 2019 Oct;
8(11):1641392.
PMID: 31646080
Granulysin is a protein present in the granules of human cytotoxic T lymphocytes (CTL) and natural killer (NK) cells, with cytolytic activity against microbes and tumors. Previous work demonstrated the...
28.
Marco-Brualla J, Al-Wasaby S, Soler R, Romanos E, Conde B, Justo-Mendez R, et al.
Cancers (Basel)
. 2019 Jul;
11(7).
PMID: 31330915
Multiprotein complexes of the mitochondrial electron transport chain form associations to generate supercomplexes. The relationship between tumor cell ability to assemble mitochondrial supercomplexes, tumorigenesis and metastasis has not been studied...
29.
Comas L, Polo E, Domingo M, Hernandez Y, Arias M, Esteban P, et al.
Materials (Basel)
. 2019 Apr;
12(7).
PMID: 30987007
Gliotoxin (GT), a secondary metabolite produced by Aspergillus molds, has been proposed as a potential anti-tumor agent. Here we have developed a nanoparticle approach to enhance delivery of GT in...
30.
Naval J, de Miguel D, Gallego-Lleyda A, Anel A, Martinez-Lostao L
Cancers (Basel)
. 2019 Apr;
11(4).
PMID: 30934872
(TNF)-related apoptosis-inducing ligand (TRAIL) is able to activate the extrinsic apoptotic pathway upon binding to DR4/TRAIL-R1 and/or DR5/TRAIL-R2 receptors. Structural data indicate that TRAIL functions as a trimer that can...