Luis Ignacio Sanchez-Abarca
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Explore the profile of Luis Ignacio Sanchez-Abarca including associated specialties, affiliations and a list of published articles.
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23
Citations
527
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Recent Articles
1.
Martinez-Carrasco R, Sanchez-Abarca L, Nieto-Gomez C, Garcia E, Sanchez-Guijo F, Argueso P, et al.
Ocul Surf
. 2019 Jan;
17(2):285-294.
PMID: 30630121
Purpose: To evaluate the therapeutic effect of subconjunctival injection of human mesenchymal stromal cells (hMSCs) in the cornea of mice with graft versus host disease (GVHD). Methods: GVHD was induced...
2.
Ibanez-Fonseca A, Ramos T, Gonzalez de Torre I, Sanchez-Abarca L, Muntion S, Javier Arias F, et al.
J Tissue Eng Regen Med
. 2017 Sep;
12(3):e1450-e1460.
PMID: 28865091
Biocompatibility studies, especially innate immunity induction, in vitro and in vivo cytotoxicity, and fibrosis, are often lacking for many novel biomaterials including recombinant protein-based ones, such as elastin-like recombinamers (ELRs),...
3.
Ramos T, Sanchez-Abarca L, Roson-Burgo B, Redondo A, Rico A, Preciado S, et al.
PLoS One
. 2017 Aug;
12(8):e0182470.
PMID: 28796790
There is evidence of continuous bidirectional cross-talk between malignant cells and bone marrow-derived mesenchymal stromal cells (BM-MSC), which favors the emergence and progression of myeloproliferative neoplastic (MPN) diseases. In the...
4.
Ramos T, Sanchez-Abarca L, Redondo A, Hernandez-Hernandez A, Almeida A, Puig N, et al.
Oncotarget
. 2017 Apr;
8(17):28187-28202.
PMID: 28390197
Histone deacetylases (HDACs) are involved in epigenetic modulation and their aberrant expression has been demonstrated in myeloproliferative neoplasms (MPN). HDAC8 inhibition has been shown to inhibit JAK2/STAT5 signaling in hematopoietic...
5.
Bejarano-Garcia J, Millan-Ucles A, Rosado I, Sanchez-Abarca L, Caballero-Velazquez T, Duran-Galvan M, et al.
Cell Death Dis
. 2016 Dec;
7(12):e2516.
PMID: 27929539
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to oxygen-limiting conditions. This adaptation includes suppression of mitochondrial activity, induction of anerobic...
6.
Martinez-Carrasco R, Sanchez-Abarca L, Nieto-Gomez C, Garcia E, Ramos T, Velasco A, et al.
Exp Eye Res
. 2016 Nov;
154:64-69.
PMID: 27818317
Dry eye disease is one of the most frequent pathological events that take place in the course of the graft versus host disease (GVHD), and is the main cause of...
7.
Barbado M, Medrano M, Caballero-Velazquez T, Alvarez-Laderas I, Sanchez-Abarca L, Garcia-Guerrero E, et al.
Int J Cancer
. 2016 Oct;
140(3):674-685.
PMID: 27778331
Although hematopoietic and immune system show high levels of the cannabinoid receptor CB2, the potential effect of cannabinoids on hematologic malignancies has been poorly determined. Here we have investigated their...
8.
Oliva-Martin M, Sanchez-Abarca L, Rodhe J, Carrillo-Jimenez A, Vlachos P, Herrera A, et al.
Oncotarget
. 2016 Jun;
7(25):37456-37470.
PMID: 27250033
In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic potential of directly targeting innate immune cell activation to limit the...
9.
Garcia-Guerrero E, Perez-Simon J, Sanchez-Abarca L, Diaz-Moreno I, De la Rosa M, Diaz-Quintana A
PLoS One
. 2016 Apr;
11(4):e0154219.
PMID: 27124285
Generating the immune response requires the discrimination of peptides presented by the human leukocyte antigen complex (HLA) through the T-cell receptor (TCR). However, how a single amino acid substitution in...
10.
Muntion S, Ramos T, Diez-Campelo M, Roson B, Sanchez-Abarca L, Misiewicz-Krzeminska I, et al.
PLoS One
. 2016 Feb;
11(2):e0146722.
PMID: 26836120
Exosomes/microvesicles (MVs) provide a mechanism of intercellular communication. Our hypothesis was that mesenchymal stromal cells (MSC) from myelodysplastic syndrome (MDS) patients could modify CD34+ cells properties by MVs. They were...