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Luis Ignacio Sanchez-Abarca

Explore the profile of Luis Ignacio Sanchez-Abarca including associated specialties, affiliations and a list of published articles. Areas
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Citations 527
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Recent Articles
11.
Ramos T, Sanchez-Abarca L, Muntion S, Preciado S, Puig N, Lopez-Ruano G, et al.
Cell Commun Signal . 2016 Jan; 14:2. PMID: 26754424
Background: Human mesenchymal stromal cells (hMSC) are multipotent cells with both regenerative and immunomodulatory activities making them an attractive tool for cellular therapy. In the last few years it has...
12.
Paiva B, Mateos M, Sanchez-Abarca L, Puig N, Vidriales M, Lopez-Corral L, et al.
Blood . 2015 Dec; 127(9):1151-62. PMID: 26668134
There is significant interest in immunotherapy for the treatment of high-risk smoldering multiple myeloma (SMM), but no available data on the immune status of this particular disease stage. Such information...
13.
Lopez-Ruano G, Prieto-Bermejo R, Ramos T, San-Segundo L, Sanchez-Abarca L, Sanchez-Guijo F, et al.
Stem Cell Reports . 2015 Sep; 5(4):516-31. PMID: 26344907
The regulation of hematopoietic stem cells (HSCs) depends on the integration of the multiple signals received from the bone marrow niche. We show the relevance of the protein tyrosine phosphatase...
14.
Ramos T, Sanchez-Abarca L, Lopez-Ruano G, Muntion S, Preciado S, Hernandez-Ruano M, et al.
Leuk Res . 2015 Jun; 39(8):921-4. PMID: 26105049
The expression of BCR-ABL in hematopoietic stem cells is a well-defined primary event in chronic myeloid leukemia (CML). Some reports have described the presence of BCR-ABL on endothelial cells from...
15.
Oliva-Martin M, Sanchez-Abarca L, Carrillo-Jimenez A, Perez-Simon J, Venero J
Anal Biochem . 2015 Apr; 480:42-8. PMID: 25892220
The study of monocyte activation and differentiation has great applications in sepsis, chronic inflammatory diseases, and cancer studies. However, despite the existence of well-established protocols for monocyte purification from human...
16.
Sanchez-Abarca L, Hernandez-Galilea E, Lorenzo R, Herrero C, Velasco A, Carrancio S, et al.
Cell Transplant . 2015 Feb; 24(12):2423-33. PMID: 25695936
Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related disorders such as graft-versus-host disease (GVHD). In the current study, we show...
17.
Sardina J, Lopez-Ruano G, Prieto-Bermejo R, Sanchez-Sanchez B, Perez-Fernandez A, Sanchez-Abarca L, et al.
Biochim Biophys Acta . 2014 Sep; 1843(12):2886-99. PMID: 25193362
PTPN13 is a high-molecular weight intracellular phosphatase with several isoforms that exhibits a highly modular structure. Although in recent years different roles have been described for PTPN13, we are still...
18.
Sanchez-Abarca L, Alvarez-Laderas I, Diez Campelo M, Caballero-Velazquez T, Herrero C, Muntion S, et al.
Cytotherapy . 2013 Mar; 15(6):673-8. PMID: 23522868
Background Aims: Mesenchymal stromal cells (MSCs) are multipotent stem cells with immunosuppressive properties. Nevertheless, it has been previously reported that MSCs might also trigger the immune response. We studied whether...
19.
Caballero-Velazquez T, Sanchez-Abarca L, Gutierrez-Cosio S, Blanco B, Calderon C, Herrero C, et al.
Haematologica . 2012 Apr; 97(9):1329-37. PMID: 22532520
Background: We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion of T cells with suppressive properties. In the current study, we analyzed...
20.
Blanco B, Sanchez-Abarca L, Caballero-Velazquez T, Santamaria C, Inoges S, Perez-Simon J
Leuk Res . 2011 Jun; 35(10):1412-5. PMID: 21658766
Current graft-versus-host disease (GVHD) inhibition approaches lead to abrogation of pathogen-specific T-cell responses. We propose an approach to inhibit GVHD without hampering immunity against pathogens: in vitro depletion of alloreactive...