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Luis I Prieto

Explore the profile of Luis I Prieto including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 113
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Recent Articles
1.
Laliberte C, Bosse B, Bourdeau V, Prieto L, Perron-Deshaies G, Vuong-Robillard N, et al.
Biomedicines . 2024 May; 12(5). PMID: 38791051
Senescent cells, which accumulate with age, exhibit a pro-inflammatory senescence-associated secretory phenotype (SASP) that includes the secretion of cytokines, lipids, and extracellular vesicles (EVs). Here, we established an in vitro...
2.
Prieto L, Sturmlechner I, Goronzy J, Baker D
Sci Transl Med . 2023 Jun; 15(699):eadg7291. PMID: 37285401
Harnessing the immunogenic potential of senescent cells may be a viable but context-dependent opportunity to boost antitumor immunity.
3.
Prieto L, Sturmlechner I, Graves S, Zhang C, Goplen N, Yi E, et al.
Cancer Cell . 2023 Jun; 41(7):1261-1275.e6. PMID: 37267954
Senescent cells play relevant but context-dependent roles during tumorigenesis. Here, in an oncogenic Kras-driven lung cancer mouse model, we found that senescent cells, specifically alveolar macrophages, accumulate early in neoplasia....
4.
Prieto L, Graves S, Baker D
Cells . 2020 Apr; 9(4). PMID: 32295081
Cellular senescence is the dynamic process of durable cell-cycle arrest. Senescent cells remain metabolically active and often acquire a distinctive bioactive secretory phenotype. Much of our molecular understanding in senescent...
5.
Prieto L, Baker D
Gerontology . 2019 Jun; 65(5):505-512. PMID: 31212284
In response to a variety of cancer-inducing stresses, cells may engage a stable cell cycle arrest mechanism, termed cellular senescence, to suppress the proliferation of preneoplastic cells. Despite this cell...