Luis Hernandez-Cano
Overview
Explore the profile of Luis Hernandez-Cano including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
33
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0
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Recent Articles
1.
Fuentes-Mateos R, Garcia-Navas R, Fernandez-Infante C, Hernandez-Cano L, Calzada-Nieto N, Olarte-San Juan A, et al.
Cell Commun Signal
. 2024 Jun;
22(1):332.
PMID: 38886790
Background: HRAS/NRAS double knockout mice exhibit exceedingly high rates of perinatal lethality due to respiratory failure caused by a significant lung maturation delay. The few animals that reach adulthood have...
2.
Fernandez-Infante C, Hernandez-Cano L, Herranz O, Berrocal P, Sicilia-Navarro C, Gonzalez-Porras J, et al.
Cell Mol Life Sci
. 2024 Feb;
81(1):84.
PMID: 38345631
C3G is a Rap1 GEF that plays a pivotal role in platelet-mediated processes such as angiogenesis, tumor growth, and metastasis by modulating the platelet secretome. Here, we explore the mechanisms...
3.
Hernandez-Cano L, Fernandez-Infante C, Herranz O, Berrocal P, Lozano F, Sanchez-Martin M, et al.
Front Cell Dev Biol
. 2022 Nov;
10:1026287.
PMID: 36393850
C3G is a Rap1 guanine nucleotide exchange factor that controls platelet activation, aggregation, and the release of α-granule content. Transgenic expression of C3G in platelets produces a net proangiogenic secretome...
4.
Marin-Quilez A, Garcia-Tunon I, Fernandez-Infante C, Hernandez-Cano L, Palma-Barqueros V, Vuelta E, et al.
Thromb Haemost
. 2021 Feb;
121(9):1193-1205.
PMID: 33626581
-related disorder (-RD) is caused by germline variants affecting the gene. This rare, heterogeneous disorder has no specific clinical or laboratory phenotype, making genetic diagnosis necessary. Although international recommendations have...
5.
Gutierrez-Herrero S, Fernandez-Infante C, Hernandez-Cano L, Ortiz-Rivero S, Guijas C, Martin-Granado V, et al.
Signal Transduct Target Ther
. 2020 Apr;
5(1):29.
PMID: 32296045
C3G is a GEF (guanine nucleotide exchange factor) for Rap GTPases, among which the isoform Rap1b is an essential protein in platelet biology. Using transgenic mouse models with platelet-specific overexpression...
6.
Ortiz-Rivero S, Baquero C, Hernandez-Cano L, Roldan-Etcheverry J, Gutierrez-Herrero S, Fernandez-Infante C, et al.
Cell Commun Signal
. 2018 Dec;
16(1):101.
PMID: 30567575
Background: Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of...