Luis G Vargas Buonfiglio
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Explore the profile of Luis G Vargas Buonfiglio including associated specialties, affiliations and a list of published articles.
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10
Citations
147
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Recent Articles
1.
Chaudhary M, Awan H, Gerard S, Bodduluri S, Comellas A, Barjaktarevic I, et al.
Am J Respir Crit Care Med
. 2025 Mar;
PMID: 40072247
Rationale: Quantifying functional small airways disease (fSAD) requires additional expiratory computed tomography (CT) scan, limiting clinical applicability. Artificial intelligence (AI) could enable fSAD quantification from chest CT scan at total...
2.
Chaudhary M, Awan H, Gerard S, Bodduluri S, Comellas A, Barjaktarevic I, et al.
medRxiv
. 2024 Sep;
PMID: 39314974
Rationale: Quantifying functional small airways disease (fSAD) requires additional expiratory computed tomography (CT) scan, limiting clinical applicability. Artificial intelligence (AI) could enable fSAD quantification from chest CT scan at total...
3.
Vargas Buonfiglio L, Vanegas Calderon O, Cano M, Simmering J, Polgreen P, Zabner J, et al.
Nutrients
. 2020 Sep;
12(9).
PMID: 32867053
Background: It is widely unknown why respiratory infections follow a seasonal pattern. Variations in ultraviolet B (UVB) light during seasons affects cutaneous synthesis of vitamin D. Serum vitamin D concentration...
4.
Vargas Buonfiglio L, Comellas A
J Thorac Dis
. 2020 Apr;
12(3):134-136.
PMID: 32274073
No abstract available.
5.
Pezzulo A, Tudas R, Stewart C, Vargas Buonfiglio L, Lindsay B, Taft P, et al.
J Clin Invest
. 2019 Jan;
129(2):744-758.
PMID: 30640172
Goblet cell metaplasia, a disabling hallmark of chronic lung disease, lacks curative treatments at present. To identify novel therapeutic targets for goblet cell metaplasia, we studied the transcriptional response profile...
6.
Vargas Buonfiglio L, Borcherding J, Frommelt M, Parker G, Duchman B, Vanegas Calderon O, et al.
Respir Res
. 2018 Mar;
19(1):42.
PMID: 29524964
Background: Smoking is a leading cause of respiratory infections worldwide. Tobacco particulate matter disrupts iron homeostasis in the lungs and increases the iron content in the airways of smokers. The...
7.
Li X, Vargas Buonfiglio L, Adam R, Stoltz D, Zabner J, Comellas A
Crit Care Med
. 2017 Sep;
45(12):e1240-e1246.
PMID: 28953499
Objectives: To determine the feasibility of using a cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770/Kalydeco, Vertex Pharmaceuticals, Boston, MA), as a therapeutic strategy for treating pulmonary edema. Design: Prospective...
8.
Vargas Buonfiglio L, Cano M, Pezzulo A, Vanegas Calderon O, Zabner J, Gerke A, et al.
BMJ Open Respir Res
. 2017 Sep;
4(1):e000211.
PMID: 28883932
Introduction: Vitamin D supplementation has been reported to prevent lung infections and increase the gene expression of antimicrobial peptides such as cathelicidin. We investigated the effect of vitamin D supplementation...
9.
Vargas Buonfiglio L, Mudunkotuwa I, Abou Alaiwa M, Vanegas Calderon O, Borcherding J, Gerke A, et al.
Environ Health Perspect
. 2017 Jul;
125(7):077003.
PMID: 28696208
Background: Sustained exposure to ambient particulate matter (PM) is a global cause of mortality. Coal fly ash (CFA) is a byproduct of coal combustion and is a source of anthropogenic...
10.
Vargas Buonfiglio L, Bagegni M, Borcherding J, Sieren J, Caraballo J, Reger A, et al.
Am J Respir Cell Mol Biol
. 2016 Aug;
55(6):869-877.
PMID: 27486964
Protein kinase Cζ (PKCζ) is highly expressed in the lung, where it plays several regulating roles in the pathogenesis of acute lung injury (ALI). Proliferation and differentiation of integrin β4...