Luis G Morelli
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Explore the profile of Luis G Morelli including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
700
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Recent Articles
1.
Arribas D, Marin-Burgin A, Morelli L
Elife
. 2023 Aug;
12.
PMID: 37584478
Heterogeneity plays an important role in diversifying neural responses to support brain function. Adult neurogenesis provides the dentate gyrus with a heterogeneous population of granule cells (GCs) that were born...
2.
Uriu K, Morelli L
Semin Cell Dev Biol
. 2023 Jan;
147:24-33.
PMID: 36631335
In development, tissue shape changes and gene expression patterns give rise to morphogenesis. Understanding tissue shape changes requires the analysis of mechanical properties of the tissue such as tissue rigidity,...
3.
Raina D, Fabris F, Morelli L, Schroter C
Development
. 2022 Feb;
149(4).
PMID: 35175328
Signal transduction networks generate characteristic dynamic activities to process extracellular signals and guide cell fate decisions such as to divide or differentiate. The differentiation of pluripotent cells is controlled by...
4.
Arancibia S, Grecco H, Morelli L
Phys Rev E
. 2022 Jan;
104(6-1):064410.
PMID: 35030833
Apoptosis is a mechanism of programmed cell death in which cells engage in a controlled demolition and prepare to be digested without damaging their environment. In normal conditions, apoptosis is...
5.
Lengyel I, Soroldoni D, Oates A, Morelli L
Pap Phys
. 2021 Jul;
6.
PMID: 34267827
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence...
6.
Uriu K, Liao B, Oates A, Morelli L
Elife
. 2021 Feb;
10.
PMID: 33587039
Integrity of rhythmic spatial gene expression patterns in the vertebrate segmentation clock requires local synchronization between neighboring cells by Delta-Notch signaling and its inhibition causes defective segment boundaries. Whether deformation...
7.
Petrungaro G, Uriu K, Morelli L
Phys Rev E
. 2019 Jul;
99(6-1):062207.
PMID: 31330742
Individual biological oscillators can synchronize to generate a collective rhythm. During vertebrate development, mobile cells exchange signals to synchronize a rhythmic pattern generator that makes the embryonic segments. Previous theoretical...
8.
Petrungaro G, Morelli L, Uriu K
Semin Cell Dev Biol
. 2018 Sep;
93:26-35.
PMID: 30261318
Embryonic morphogenesis is organized by an interplay between intercellular signaling and cell movements. Both intercellular signaling and cell movement involve multiple timescales. A key timescale for signaling is the time...
9.
Jorg D, Morelli L, Julicher F
Phys Rev E
. 2018 May;
97(3-1):032409.
PMID: 29776186
We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize...
10.
Lleras Forero L, Narayanan R, Huitema L, VanBergen M, Apschner A, Peterson-Maduro J, et al.
Elife
. 2018 Apr;
7.
PMID: 29624170
Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role...