Luis Carlos Lopez
Overview
Explore the profile of Luis Carlos Lopez including associated specialties, affiliations and a list of published articles.
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20
Citations
814
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Recent Articles
1.
Pesini A, Barriocanal-Casado E, Monzio Compagnoni G, Hidalgo-Gutierrez A, Yanez G, Bakkali M, et al.
Free Radic Biol Med
. 2025 Jan;
229:441-457.
PMID: 39788391
Coenzyme Q (CoQ) is a critical component of the mitochondrial respiratory chain. CoQ deficiencies cause a variety of clinical syndromes, often involving encephalopathies. The heterogeneity of clinical manifestations implies different...
2.
Fabra M, Paredes-Fuentes A, Torralba Carnerero M, Moreno Fernandez de Ayala D, Arroyo Luque A, Sanchez Cuesta A, et al.
J Inherit Metab Dis
. 2024 Jul;
47(5):1047-1068.
PMID: 38973597
The protein encoded by COQ7 is required for CoQ synthesis in humans, hydroxylating 3-demethoxyubiquinol (DMQ) in the second to last steps of the pathway. COQ7 mutations lead to a primary...
3.
Aragon-Vela J, Casuso R, Aparisi A, Plaza-Diaz J, Rueda-Robles A, Hidalgo-Gutierrez A, et al.
J Physiol
. 2024 Apr;
602(21):5631-5641.
PMID: 38630964
In eukaryotic cells, aerobic energy is produced by mitochondria through oxygen uptake. However, little is known about the early mitochondrial responses to moderate hypobaric hypoxia (MHH) in highly metabolic active...
4.
Monfrini E, Pesini A, Biella F, Sobreira C, Emmanuele V, Brescia G, et al.
Neurol Genet
. 2023 Apr;
9(2):e200058.
PMID: 37090936
Background And Objectives: Coenzyme Q (CoQ)-deficient cerebellar ataxia can be due to pathogenic variants in genes encoding for CoQ biosynthetic proteins or associated with defects in protein unrelated to its...
5.
Hidalgo-Gutierrez A, Barriocanal-Casado E, Diaz-Casado M, Gonzalez-Garcia P, Chiozzi R, Acuna-Castroviejo D, et al.
Biomedicines
. 2021 Oct;
9(10).
PMID: 34680574
Primary mitochondrial diseases are caused by mutations in mitochondrial or nuclear genes, leading to the abnormal function of specific mitochondrial pathways. Mitochondrial dysfunction is also a secondary event in more...
6.
Borges T, Serna A, Lopez L, Lara L, Nieto R, Seiquer I
Antioxidants (Basel)
. 2019 Aug;
8(7).
PMID: 31373316
The health benefits of extra virgin olive oil (EVOO) are related to its chemical composition and the presence of bioactive compounds with antioxidant properties. The aim of this study was...
7.
Casuso R, Al-Fazazi S, Hidalgo-Gutierrez A, Lopez L, Plaza-Diaz J, Rueda-Robles A, et al.
Free Radic Biol Med
. 2019 Jan;
134:304-310.
PMID: 30685403
Hydroxytyrosol (HT) has been demonstrated to improve mitochondrial function, both in sedentary and in exercised animals. Herein, we assessed the effects of two different doses of HT on exercise-induced mitochondrial...
8.
Mendivil-Perez M, Soto-Mercado V, Guerra-Librero A, Fernandez-Gil B, Florido J, Shen Y, et al.
J Pineal Res
. 2017 Apr;
63(2).
PMID: 28423196
Neural stem cells (NSCs) are regarded as a promising therapeutic approach to protecting and restoring damaged neurons in neurodegenerative diseases (NDs) such as Parkinson's disease and Alzheimer's disease (PD and...
9.
Fernandez-Gil B, Abdel Moneim A, Ortiz F, Shen Y, Soto-Mercado V, Mendivil-Perez M, et al.
PLoS One
. 2017 Apr;
12(4):e0174474.
PMID: 28403142
Radiotherapy-induced gut toxicity is among the most prevalent dose-limiting toxicities following radiotherapy. Prevention of radiation enteropathy requires protection of the small intestine. However, despite the prevalence and burden of this...
10.
Fernandez-Mosquera L, Diogo C, Yambire K, Santos G, Luna Sanchez M, Benit P, et al.
Sci Rep
. 2017 Mar;
7:45076.
PMID: 28345620
Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we...