Luigi Nezi
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Explore the profile of Luigi Nezi including associated specialties, affiliations and a list of published articles.
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46
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3745
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Recent Articles
1.
Ballerini M, Galie S, Tyagi P, Catozzi C, Raji H, Nabinejad A, et al.
Nat Biomed Eng
. 2025 Feb;
PMID: 39939548
Patient responses to immune checkpoint inhibitors can be influenced by the gastrointestinal microbiome. Mouse models can be used to study microbiome-host crosstalk, yet their utility is constrained by substantial anatomical,...
2.
Macandog A, Catozzi C, Capone M, Nabinejad A, Nanaware P, Liu S, et al.
Cell Host Microbe
. 2024 Oct;
32(11):2004-2018.e9.
PMID: 39481388
Immune checkpoint inhibitors (ICIs) improve outcomes in advanced melanoma, but many patients are refractory or experience relapse. The gut microbiota modulates antitumor responses. However, inconsistent baseline predictors point to heterogeneity...
3.
Palma C, Aterini B, Ferrari E, Mangione M, Romeo M, Nezi L, et al.
Biofabrication
. 2024 Sep;
17(1).
PMID: 39332448
The dysregulation of the immune system plays a crucial role in the pathogenesis of manyfold diseases, among which we find rheumatoid arthritis (RA), an autoimmune disease characterized by chronic inflammation...
4.
Pallavicini I, Frasconi T, Catozzi C, Ceccacci E, Tiberti S, Haas D, et al.
Nat Commun
. 2024 Aug;
15(1):7366.
PMID: 39191730
The lysine-specific histone demethylase 1 A (LSD1) is involved in antitumor immunity; however, its role in shaping CD8 + T cell (CTL) differentiation and function remains largely unexplored. Here, we...
5.
Dallavilla T, Galie S, Sambruni G, Borin S, Fazio N, Fumagalli-Romario U, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Jun;
1870(7):167311.
PMID: 38909851
Tumours exhibit significant heterogeneity in their molecular profiles across patients, largely influenced by the tissue of origin, where certain driver gene mutations are predominantly associated with specific cancer types. Here,...
6.
Bjork J, Bolte L, Thomas A, Lee K, Rossi N, Wind T, et al.
Nat Med
. 2024 Feb;
30(3):785-796.
PMID: 38365950
Multiple clinical trials targeting the gut microbiome are being conducted to optimize treatment outcomes for immune checkpoint blockade (ICB). To improve the success of these interventions, understanding gut microbiome changes...
7.
Lazzaroni F, Meessen J, Sun Y, Lanfranconi S, Scola E, DAlessandris Q, et al.
EBioMedicine
. 2023 Dec;
99:104914.
PMID: 38113759
Background: Cerebral Cavernous Malformation (CCM) is a rare cerebrovascular disease, characterized by the presence of multiple vascular malformations that may result in intracerebral hemorrhages (ICHs), seizure(s), or focal neurological deficits...
8.
Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang C, et al.
Nat Metab
. 2023 Aug;
5(9):1563-1577.
PMID: 37653041
In the tumor microenvironment, adipocytes function as an alternate fuel source for cancer cells. However, whether adipocytes influence macromolecular biosynthesis in cancer cells is unknown. Here we systematically characterized the...
9.
Galie S, Nezi L
Cell Host Microbe
. 2023 Jun;
31(6):919-920.
PMID: 37321175
The use of bacterial colonists as therapy carriers is gaining interest for treating cancer. In a recent publication in Science, the work by Chen et al. proposes the engineering of...
10.
Nezi L, Manzo T
Cell Metab
. 2023 Jun;
35(6):907-909.
PMID: 37285805
The composition of nutrients in the tumor microenvironment is a key determinant of anti-tumor CD8 T cell response. In this issue of Cell Metabolism, Jiang and colleagues unveil that tumor-derived...