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Ludwig Knabl

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Articles 45
Citations 404
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Recent Articles
1.
Brangel P, Tureli S, Muhlemann B, Liechti N, Zysset D, Engler O, et al.
Viruses . 2025 Jan; 16(12). PMID: 39772242
Setting up a global SARS-CoV-2 surveillance system requires an understanding of how virus isolation and propagation practices, use of animal or human sera, and different neutralisation assay platforms influence assessment...
2.
Rossler A, Netzl A, Knabl L, Wilks S, Muhlemann B, Tureli S, et al.
NPJ Vaccines . 2024 May; 9(1):85. PMID: 38762525
Antigenic characterization of newly emerging SARS-CoV-2 variants is important to assess their immune escape and judge the need for future vaccine updates. To bridge data obtained from animal sera with...
3.
Schatz C, Knabl L, Lee H, Seeboeck R, von Laer D, Lafon E, et al.
Microorganisms . 2024 Apr; 12(4). PMID: 38674742
The global dissemination of SARS-CoV-2 resulted in the emergence of several variants, including Alpha, Alpha + E484K, Beta, and Omicron. Our research integrated the study of eukaryotic translation factors and...
4.
Hoffmann M, Willruth L, Dietrich A, Lee H, Knabl L, Trummer N, et al.
Sci Rep . 2024 Feb; 14(1):2808. PMID: 38307916
Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in biomedical research but is still rarely used in clinical practice. In this study, we propose that...
5.
Hoffmann M, Willruth L, Dietrich A, Lee H, Knabl L, Trummer N, et al.
bioRxiv . 2023 Dec; PMID: 38076885
Bulk RNA sequencing (RNA-seq) of blood is typically used for gene expression analysis in biomedical research but is still rarely used in clinical practice. In this study, we argue that...
6.
Eichhorn T, Weiss R, Huber S, Ebeyer-Masotta M, Mostageer M, Emprechtinger R, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38069209
Severe COVID-19 is frequently associated with thromboembolic complications. Increased platelet activation and platelet-leukocyte aggregate formation can amplify thrombotic responses by inducing tissue factor (TF) expression on leukocytes. Here, we characterized...
7.
Rossler A, Knabl L, Netzl A, Bante D, Borena W, von Laer D, et al.
J Infect Dis . 2023 Nov; 229(3):644-647. PMID: 38016020
We analyzed neutralizing antibodies in samples from ancestral + BA.1 and ancestral + BA.4/5 boosted individuals, collected around 5.5 months after booster. Titers of neutralizing antibodies generally decreased compared to...
8.
Schenk H, Caf Y, Knabl L, Mayerhofer C, Rauch W
Sci Rep . 2023 Nov; 13(1):18910. PMID: 37919330
Demand for mass surveillance during peak times of the SARS-CoV-2 pandemic caused high workload for clinical laboratories. Efficient and cost conserving testing designs by means of group testing can substantially...
9.
Rossler A, Netzl A, Knabl L, Bante D, Wilks S, Borena W, et al.
Nat Commun . 2023 Aug; 14(1):5224. PMID: 37633965
Since emergence of the initial SARS-CoV-2 BA.1, BA.2 and BA.5 variants, Omicron has diversified substantially. Antigenic characterization of these new variants is important to analyze their potential immune escape from...
10.
Sonnleitner S, Walder S, Knabl L, Poernbacher R, Tschurtschenthaler T, Hinterbichler E, et al.
Front Immunol . 2023 May; 14:1165769. PMID: 37256137
Background: Immune imprinting is a phenomenon in which a person's immune system develops a specific immunological memory of the pathogen or vaccine due to a previous exposure. This memory basically...