Ludovic J Chassin
Overview
Explore the profile of Ludovic J Chassin including associated specialties, affiliations and a list of published articles.
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19
Citations
874
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Recent Articles
1.
Wilinska M, Blaha J, Chassin L, Cordingley J, Dormand N, Ellmerer M, et al.
Diabetes Technol Ther
. 2011 Apr;
13(7):713-22.
PMID: 21488803
Background: Numerous guidelines and algorithms exist to achieve glycemic control. Their strengths and weaknesses are difficult to assess without head-to-head comparison in time-consuming clinical trials. We hypothesized that computer simulations...
2.
Wilinska M, Chassin L, Acerini C, Allen J, Dunger D, Hovorka R
J Diabetes Sci Technol
. 2010 Feb;
4(1):132-44.
PMID: 20167177
Background: Closed-loop insulin delivery systems linking subcutaneous insulin infusion to real-time continuous glucose monitoring need to be evaluated in humans, but progress can be accelerated with the use of in...
3.
Hovorka R, Allen J, Elleri D, Chassin L, Harris J, Xing D, et al.
Lancet
. 2010 Feb;
375(9716):743-51.
PMID: 20138357
Background: Closed-loop systems link continuous glucose measurements to insulin delivery. We aimed to establish whether closed-loop insulin delivery could control overnight blood glucose in young people. Methods: We undertook three...
4.
Wilinska M, Chassin L, Hovorka R
J Diabetes Sci Technol
. 2009 Nov;
2(3):417-23.
PMID: 19885206
Background: In silico testing was used extensively in the European Commission-funded Closed Loop Insulin Infusion for Critically Ill Patients (Clinicip) project, which aimed to develop prototype systems for closed loop...
5.
Cordingley J, Vlasselaers D, Dormand N, Wouters P, Squire S, Chassin L, et al.
Intensive Care Med
. 2008 Jul;
35(1):123-8.
PMID: 18661120
Objective: To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h,...
6.
Hovorka R, Chassin L, Ellmerer M, Plank J, Wilinska M
Physiol Meas
. 2008 Jul;
29(8):959-78.
PMID: 18641427
Focused research is underway to improve the delivery of tight glycaemic control at the intensive care unit. A major component is the development of safe, efficacious and effective insulin titration...
7.
Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients
Pachler C, Plank J, Weinhandl H, Chassin L, Wilinska M, Kulnik R, et al.
Intensive Care Med
. 2008 Feb;
34(7):1224-30.
PMID: 18297268
Objective: Tight glycaemic control (TGC) in critically ill patients improves clinical outcome, but is difficult to establish The primary objective of the present study was to compare glucose control in...
8.
Wilinska M, Chassin L, Hovorka R
Conf Proc IEEE Eng Med Biol Soc
. 2007 Oct;
2006:67-70.
PMID: 17946380
Tight glycaemic control has been shown to reduce mortality and morbidity in critically ill subjects. Using in silico computational approach, the objective of this study was to evaluate the effect...
9.
Hovorka R, Kremen J, Blaha J, Matias M, Anderlova K, Bosanska L, et al.
J Clin Endocrinol Metab
. 2007 Jun;
92(8):2960-4.
PMID: 17550955
Context: Elevated blood glucose levels occur frequently in the critically ill. Tight glucose control by intensive insulin treatment markedly improves clinical outcome. Objective And Design: This is a randomized controlled...
10.
Plank J, Blaha J, Cordingley J, Wilinska M, Chassin L, Morgan C, et al.
Diabetes Care
. 2006 Jul;
29(8):1987-8.
PMID: 16873824
No abstract available.