Ludovic Benard
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Explore the profile of Ludovic Benard including associated specialties, affiliations and a list of published articles.
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20
Citations
914
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Recent Articles
1.
Cacheux M, Strauss B, Raad N, Ilkan Z, Hu J, Benard L, et al.
Circ Arrhythm Electrophysiol
. 2019 Nov;
12(11):e007382.
PMID: 31726860
Background: STIM1 (stromal interaction molecule 1) is a calcium (Ca) sensor that regulates cardiac hypertrophy by triggering store-operated Ca entry. Because STIM1 binding to phospholamban increases sarcoplasmic reticulum Ca load...
2.
Rodriguez P, Sassi Y, Troncone L, Benard L, Ishikawa K, Gordon R, et al.
Eur Heart J
. 2018 Apr;
40(12):967-978.
PMID: 29668883
Aims: Myocardial fibrosis is associated with profound changes in ventricular architecture and geometry, resulting in diminished cardiac function. There is currently no information on the role of the delta-like homologue...
3.
Chamberlain K, Riyad J, Garnett T, Kohlbrenner E, Mookerjee A, Elmastour F, et al.
Hum Gene Ther
. 2018 Apr;
29(8):927-937.
PMID: 29641321
Adeno-associated virus serotype 9 (AAV9) is an efficient vector for gene transfer to the myocardium. However, the use of ubiquitous promoters, such as the cytomegalovirus (CMV) promoter, can result in...
4.
Evrard S, Lecce L, Michelis K, Nomura-Kitabayashi A, Pandey G, Purushothaman K, et al.
Nat Commun
. 2017 Feb;
8:14710.
PMID: 28205517
No abstract available.
5.
Chen J, Hammoudi N, Benard L, Ceholski D, Zhang S, Lebeche D, et al.
Cardiovasc Pharm Open Access
. 2016 Dec;
5(5).
PMID: 27917392
In the present study, we explore the inherent variability that leads to overlaps in cardiac functional parameters between control and post-myocardial infarction (MI) mice. Heart failure was induced by Left...
6.
Evrard S, Lecce L, Michelis K, Nomura-Kitabayashi A, Pandey G, Purushothaman K, et al.
Nat Commun
. 2016 Jun;
7:11853.
PMID: 27340017
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells including fibroblasts are prominent in atherosclerosis, with key...
7.
La Merrill M, Sethi S, Benard L, Moshier E, Haraldsson B, Buettner C
Environ Health Perspect
. 2016 Jun;
124(11):1722-1727.
PMID: 27325568
Background: Dichlorodiphenyltrichloroethane (DDT) was used extensively to control malaria, typhus, body lice, and bubonic plague worldwide, until countries began restricting its use in the 1970s. However, the use of DDT...
8.
Benard L, Oh J, Cacheux M, Lee A, Nonnenmacher M, Matasic D, et al.
Circulation
. 2016 Mar;
133(15):1458-71.
PMID: 26936863
Background: Stromal interaction molecule 1 (STIM1) is a dynamic calcium signal transducer implicated in hypertrophic growth of cardiomyocytes. STIM1 is thought to act as an initiator of cardiac hypertrophic response...
9.
Chaanine A, Gordon R, Nonnenmacher M, Kohlbrenner E, Benard L, Hajjar R
Physiol Rep
. 2015 Jul;
3(7).
PMID: 26152691
Autophagy, macroautophagy and chaperone-mediated autophagy (CMA), are upregulated in pressure overload (PO) hypertrophy. In this study, we targeted this process at its induction using 3 methyladenine and at the lysosomal...
10.
Cook J, Carta L, Benard L, Chemaly E, Chiu E, Rao S, et al.
J Clin Invest
. 2014 Feb;
124(3):1329-39.
PMID: 24531548
Patients with Marfan syndrome (MFS), a multisystem disorder caused by mutations in the gene encoding the extracellular matrix (ECM) protein fibrillin 1, are unusually vulnerable to stress-induced cardiac dysfunction. The...