Ludger Klein-Hitpass
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Explore the profile of Ludger Klein-Hitpass including associated specialties, affiliations and a list of published articles.
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123
Citations
3710
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Recent Articles
31.
Wallner S, Schroder C, Leitao E, Berulava T, Haak C, Beisser D, et al.
Epigenetics Chromatin
. 2016 Aug;
9:33.
PMID: 27478504
Background: Monocyte-to-macrophage differentiation involves major biochemical and structural changes. In order to elucidate the role of gene regulatory changes during this process, we used high-throughput sequencing to analyze the complete...
32.
Sellmann L, Scholtysik R, de Beer D, Eisele L, Klein-Hitpass L, Nuckel H, et al.
Leuk Lymphoma
. 2015 Oct;
57(3):590-5.
PMID: 26457386
This study investigated the correlation of the extent of chromosomal aberrations including uniparental disomies (UPDs) by SNP-chip analysis and FISH to telomere length in 46 patients with CLL. CLL harboring...
33.
Jeruschke S, Jeruschke K, DiStasio A, Karaterzi S, Buscher A, Nalbant P, et al.
PLoS One
. 2015 Sep;
10(9):e0137043.
PMID: 26331477
Background: Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a...
34.
Johansson P, Bergmann A, Rahmann S, Wohlers I, Scholtysik R, Przekopowitz M, et al.
Int J Cancer
. 2015 Jul;
138(1):121-4.
PMID: 26199174
The pathogenesis of T-cell large granular lymphocytic leukemia (T-LGL) is poorly understood, as STAT3 mutations are the only known frequent genetic lesions. Here, we identified non-synonymous alterations in the TNFAIP3...
35.
Lindner S, Bachmann H, Odersky A, Schaefers S, Klein-Hitpass L, Hero B, et al.
Biomed Rep
. 2015 Jul;
3(4):443-446.
PMID: 26171145
Maintenance of telomere length is a critical hallmark of malignant transformation. While silenced in somatic cells, telomerase reverse transcriptase (TERT), the catalytic subunit of telomerase, is frequently overexpressed in malignant...
36.
Li Y, Durig J, Gobel M, Hanoun M, Klein-Hitpass L, Duhrsen U
Int J Hematol
. 2015 Jul;
102(3):278-88.
PMID: 26121956
In bone marrow malignancies, little is known about the fate of stromal cells after replacement of normal cells by neoplastic hematopoietic ones. In this study, fibroblasts from patients with acute...
37.
Steinert A, Kunz M, Prager P, Gobel S, Klein-Hitpass L, Ebert R, et al.
Stem Cell Res Ther
. 2015 Jun;
6:114.
PMID: 26036250
Introduction: The bursa subacromialis (BS) provides the gliding mechanism of the shoulder and regenerates itself after surgical removal. Therefore, we explored the presence of mesenchymal stem cells (MSCs) within the...
38.
Graser S, Mentrup B, Schneider D, Klein-Hitpass L, Jakob F, Hofmann C
Bone
. 2015 Jun;
79:150-61.
PMID: 26032516
Patients suffering from the rare hereditary disease hypophosphatasia (HPP), which is based on mutations in the ALPL gene, tend to develop central nervous system (CNS) related issues like epileptic seizures...
39.
Harati K, Slodnik P, Chromik A, Goertz O, Hirsch T, Kapalschinski N, et al.
Anticancer Res
. 2015 Feb;
35(2):767-74.
PMID: 25667456
Background/aim: Metastatic fibrosarcomas still represent a therapeutic dilemma. Commonly used chemotherapeutic agents such as doxorubicin have been proven effective in fewer than 30% of all cases disseminated of fibrosarcoma. Elderly...
40.
Harati K, Slodnik P, Chromik A, Behr B, Goertz O, Hirsch T, et al.
Int J Oncol
. 2015 Jan;
46(4):1629-36.
PMID: 25625225
Complete surgical resection with clear margins remains the mainstay of therapy for localised fibrosarcomas. Nevertheless, metastatic fibrosarcomas still represent a therapeutic dilemma. Commonly used chemotherapeutic agents like doxorubicin have proven...