Ludger A Wessjohann
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Explore the profile of Ludger A Wessjohann including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Reguera L, Vasco A, Marrero J, Ricardo M, Wessjohann L, Rivera D
J Am Chem Soc
. 2025 Mar;
147(10):8478-8487.
PMID: 40035137
The ability to chemoselectively modify either the peptide backbone or specific side chains is critical to advance the fields of bioconjugation and peptide pharmaceuticals. Transition-metal catalysis has been widely used...
2.
Kappen J, Rashan L, Franke K, Wessjohann L
Molecules
. 2025 Feb;
30(4).
PMID: 40005262
Several polyphenol-rich species (Combretaceae) are known to accelerate wound healing. Recently, the Omani medicinal plant (now ) was attributed to the genus based on phylogenetic studies. Leaves, bark, and extracts...
3.
Cyclic Lipopeptides as Selective Anticancer Agents: In vitro Efficacy on B16F10 Mouse Melanoma Cells
Hmedat A, Morejon M, Rivera D, Pantelic N, Wessjohann L, Kaluderovic G
Anticancer Agents Med Chem
. 2025 Jan;
PMID: 39851102
Objective: In this study, 25 synthetic cyclic lipopeptides (CLPs) were investigated for their anticancer potential against mouse melanoma (B16F10) cells, human prostate cancer (PC-3), human colorectal adenocarcinoma (HT-29) and mouse...
4.
Herrera-Rocha F, Fernandez-Nino M, Duitama J, Cala M, Chica M, Wessjohann L, et al.
J Cheminform
. 2024 Dec;
16(1):140.
PMID: 39658805
Flavor is the main factor driving consumers acceptance of food products. However, tracking the biochemistry of flavor is a formidable challenge due to the complexity of food composition. Current methodologies...
5.
Llanes D, Rennert R, Janicke P, Morgan I, Reguera L, Rivera D, et al.
Front Pharmacol
. 2024 Nov;
15:1408091.
PMID: 39600359
Peptide-drug conjugates (PDCs) have recently gained significant attention for the targeted delivery of anticancer therapeutics, mainly due to their cost-effective and chemically defined production and lower antigenicity compared to ADCs,...
6.
Eldehna W, Fares M, Bonardi A, Avgenikos M, Baselious F, Schmidt M, et al.
J Med Chem
. 2024 Nov;
67(22):20438-20454.
PMID: 39550697
Hypoxia in tumors contributes to chemotherapy resistance, worsened by acidosis driven by carbonic anhydrases (CA IX and XII). Targeting these enzymes can mitigate acidosis, thus enhancing tumor sensitivity to cytotoxic...
7.
Mamadalieva N, Soral M, Kysil E, Stark P, Frolov A, Wessjohann L
Sci Rep
. 2024 Nov;
14(1):28179.
PMID: 39548128
Ajuga turkestanica preparations are used as anti-aging cosmeceuticals and for medicinal purposes. Herein we describe the characterization and quantification of its metabolites in different organs using UHPLC-MS and NMR spectroscopy....
8.
Morgan I, Rennert R, Berger R, Jelaca S, Maksimovic-Ivanic D, Dunderovic D, et al.
Sci Rep
. 2024 Nov;
14(1):28126.
PMID: 39548116
Quinazolinones, particularly 9-azaglycophymines, and closely related derivatives and precursors were tested in vitro against various breast cancer cell lines representing the major types of breast tumors. Among the 49 compounds...
9.
Saoud M, Grau J, Rennert R, Mueller T, Yousefi M, Davari M, et al.
Adv Sci (Weinh)
. 2024 Oct;
11(47):e2404085.
PMID: 39431333
A bottleneck in the development of new anti-cancer drugs is the recognition of their mode of action (MoA). Metabolomics combined with machine learning allowed to predict MoAs of novel anti-proliferative...
10.
Farag M, Saied D, Afifi S, Kunzmann A, Wessjohann L, Westphal H, et al.
J Adv Res
. 2024 Oct;
PMID: 39414229
Introduction: Climate change poses various threats to marine life, particularly in shallow tropical waters. Objective: The impact of increased temperature and ultraviolet (UV) exposure on two photosymbiotic cnidarians, a common...