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Lucy J Leiper

Explore the profile of Lucy J Leiper including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 434
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Recent Articles
1.
Kucerova R, Dora N, Mort R, Wallace K, Leiper L, Lowes C, et al.
Mol Vis . 2012 Jan; 18:139-50. PMID: 22275805
Purpose: To investigate the roles of intracellular signaling elicited by Hedgehog (Hh) ligands in corneal maintenance and wound healing. Methods: The expression of Hedgehog pathway components in the cornea was...
2.
Kucerova R, Walczysko P, Reid B, Ou J, Leiper L, Rajnicek A, et al.
J Cell Physiol . 2010 Oct; 226(6):1544-53. PMID: 20945376
Ion flow from intact tissue into epithelial wound sites results in lateral electric currents that may represent a major driver of wound healing cell migration. Use of applied electric fields...
3.
Marek C, Wallace K, Durward E, Koruth M, Leel V, Leiper L, et al.
Comp Hepatol . 2009 May; 8:1. PMID: 19432992
Background: Pregnane X receptor (PXR) agonists inhibit liver fibrosis. However, the rodent PXR activator pregnenolone 16alpha carbonitrile (PCN) blocks, in vitro, hepatic stellate cell-to-myofibroblast trans-differentiation and proliferation in cells from...
4.
Leiper L, Ou J, Walczysko P, Kucerova R, Lavery D, West J, et al.
Invest Ophthalmol Vis Sci . 2008 Nov; 50(3):1122-8. PMID: 19029029
Purpose: Corneal nerves play essential roles in maintaining the ocular surface through provision of neurotrophic support, but genetic control of corneal innervation is poorly understood. The possibility of a neurotrophic...
5.
Kucerova R, Ou J, Lawson D, Leiper L, Collinson J
Invest Ophthalmol Vis Sci . 2006 Nov; 47(12):5276-82. PMID: 17122113
Purpose: Congenital aniridia due to heterozygosity for Pax6 is associated with ocular surface disease, including keratopathy. This study investigated how defects in glycoconjugate component of the cell surface of Pax6+/-...
6.
Ambati B, Nozaki M, Singh N, Takeda A, Jani P, Suthar T, et al.
Nature . 2006 Oct; 443(7114):993-7. PMID: 17051153
Corneal avascularity-the absence of blood vessels in the cornea-is required for optical clarity and optimal vision, and has led to the cornea being widely used for validating pro- and anti-angiogenic...
7.
Leiper L, Walczysko P, Kucerova R, Ou J, Shanley L, Lawson D, et al.
BMC Biol . 2006 Aug; 4:27. PMID: 16914058
Background: Congenital aniridia caused by heterozygousity at the PAX6 locus is associated with ocular surface disease including keratopathy. It is not clear whether the keratopathy is a direct result of...