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Lucrezia Rinaldi

Explore the profile of Lucrezia Rinaldi including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 227
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Recent Articles
1.
Ummarino S, Poluben L, Ebralidze A, Autiero I, Ebralidze A, Zhang Y, et al.
Res Sq . 2025 Feb; PMID: 39975922
Coordinated initiation of DNA replication is essential to ensure efficient and timely DNA synthesis. Yet, molecular mechanism describing how replication initiation is coordinated in eukaryotic cells is not completely understood....
2.
Esposito C, Autiero I, Sandomenico A, Li H, Bassal M, Ibba M, et al.
Nat Commun . 2023 Jan; 14(1):99. PMID: 36609400
DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has been limited to the...
3.
Ummarino S, Hausman C, Gaggi G, Rinaldi L, Bassal M, Zhang Y, et al.
Cells . 2021 Nov; 10(11). PMID: 34831209
Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal cell development via as yet unknown molecular mechanisms. Consequently, imbalance in the nutritional intake is able to dysregulate...
4.
Wilmerding A, Bouteille L, Rinaldi L, Caruso N, Graba Y, Delfini M
Int J Mol Sci . 2021 Aug; 22(16). PMID: 34445617
HOX transcription factors are members of an evolutionarily conserved family of proteins required for the establishment of the anteroposterior body axis during bilaterian development. Although they are often deregulated in...
5.
Wilmerding A, Rinaldi L, Caruso N, Lo Re L, Bonzom E, Saurin A, et al.
Development . 2021 Jan; 148(4). PMID: 33472847
Differential Hox gene expression is central for specification of axial neuronal diversity in the spinal cord. Here, we uncover an additional function of Hox proteins in the developing spinal cord,...
6.
Rinaldi L, Saurin A, Graba Y
Int J Dev Biol . 2019 Jan; 62(11-12):755-766. PMID: 30604845
The functional identification and dissection of protein domains has been a successful approach towards the understanding of Hox protein specificity. However, only a few functional protein domains have been identified;...
7.
Crocker J, Abe N, Rinaldi L, McGregor A, Frankel N, Wang S, et al.
Cell . 2015 Jan; 160(1-2):191-203. PMID: 25557079
In animals, Hox transcription factors define regional identity in distinct anatomical domains. How Hox genes encode this specificity is a paradox, because different Hox proteins bind with high affinity in ...