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Lucila Ohno-Machado

Explore the profile of Lucila Ohno-Machado including associated specialties, affiliations and a list of published articles. Areas
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Articles 311
Citations 6022
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Recent Articles
1.
Xie Q, Chen Q, Chen A, Peng C, Hu Y, Lin F, et al.
NPJ Digit Med . 2025 Mar; 8(1):141. PMID: 40044845
Recent advancements in large language models (LLMs) show significant potential in medical applications but are hindered by limited specialized medical knowledge. We present Me-LLaMA, a family of open-source medical LLMs...
2.
Pham A, El-Kareh R, Myers F, Ohno-Machado L, Kuo T
Heliyon . 2025 Feb; 11(1):e41350. PMID: 39958729
Background: infection is a major health threat. Healthcare institutions have strong medical and financial incentives to keep infections under control. Blanket testing at admission is in general not recommended, and...
3.
Kuo T, Gabriel R, Koola J, Schooley R, Ohno-Machado L
Nat Commun . 2025 Feb; 16(1):1371. PMID: 39910076
Quality improvement, clinical research, and patient care can be supported by medical predictive analytics. Predictive models can be improved by integrating more patient records from different healthcare centers (horizontal) or...
4.
Demarais Z, Conlon C, Rivier C, Clocchiatti-Tuozzo S, Renedo D, Torres-Lopez V, et al.
Neurology . 2025 Jan; 104(4):e210276. PMID: 39889253
Background And Objectives: Type 2 diabetes mellitus (T2DM) is highly genetically determined, and polygenic susceptibility to T2DM (PSD) increases the risk of worse glycemic control and adverse vascular outcomes. Its...
5.
Xie Q, Chen Q, Chen A, Peng C, Hu Y, Lin F, et al.
Res Sq . 2025 Jan; PMID: 39764122
Recent advancements in large language models (LLMs) like ChatGPT and LLaMA have shown significant potential in medical applications, but their effectiveness is limited by a lack of specialized medical knowledge...
6.
Koola J, Ramesh K, Mao J, Ahn M, Davis S, Govindarajulu U, et al.
J Am Med Inform Assoc . 2024 Oct; 32(1):206-217. PMID: 39471493
Objectives: Traditional methods for medical device post-market surveillance often fail to accurately account for operator learning effects, leading to biased assessments of device safety. These methods struggle with non-linearity, complex...
7.
Durant T, Knight E, Nelson B, Dudgeon S, Lee S, Walliman D, et al.
J Am Med Inform Assoc . 2024 Jun; 31(8):1774-1784. PMID: 38934288
Objectives: To introduce quantum computing technologies as a tool for biomedical research and highlight future applications within healthcare, focusing on its capabilities, benefits, and limitations. Target Audience: Investigators seeking to...
8.
Xie Q, Chen Q, Chen A, Peng C, Hu Y, Lin F, et al.
Res Sq . 2024 Jun; PMID: 38826372
Recent advancements in large language models (LLMs) such as ChatGPT and LLaMA have hinted at their potential to revolutionize medical applications, yet their application in clinical settings often reveals limitations...
9.
Lacson R, Yu Y, Kuo T, Ohno-Machado L
J Am Med Inform Assoc . 2024 May; 31(6):1423-1435. PMID: 38726710
Objective: Blockchain has emerged as a potential data-sharing structure in healthcare because of its decentralization, immutability, and traceability. However, its use in the biomedical domain is yet to be investigated...
10.
Stead W, Miller R, Ohno-Machado L, Bakken S
J Am Med Inform Assoc . 2023 Dec; 31(1):1-9. PMID: 38134400
No abstract available.