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Lucila A Acevedo

Explore the profile of Lucila A Acevedo including associated specialties, affiliations and a list of published articles. Areas
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Citations 82
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Recent Articles
1.
Nguyen D, Lin L, Zhou J, Kibby E, Sia T, Tillis T, et al.
Biochemistry . 2020 Dec; 59(50):4755-4765. PMID: 33272017
In the MAPK pathway, an oncogenic V600E mutation in B-Raf kinase causes the enzyme to be constitutively active, leading to aberrantly high phosphorylation levels of its downstream effectors, MEK and...
2.
Barbosa R, Acevedo L, Marmorstein R
Mol Cancer Res . 2020 Nov; 19(3):361-374. PMID: 33139506
The RAS-RAF-MEK-ERK pathway is the most well-studied of the MAPK cascades and is critical for cell proliferation, differentiation, and survival. Abnormalities in regulation resulting from mutations in components of this...
3.
Fisher C, Resnick R, De S, Acevedo L, Lu K, Schroeder F, et al.
J Alzheimers Dis . 2016 Sep; 55(1):391-410. PMID: 27662285
The cis/trans isomerization of X-Pro peptide bonds in proteins in some instances acts as a molecular switch in biological pathways. Our prior work suggests that the cis isomer of the...