Lucie Valek
Overview
Explore the profile of Lucie Valek including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
153
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0
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Recent Articles
11.
Hardt S, Valek L, Zeng-Brouwers J, Wilken-Schmitz A, Schaefer L, Tegeder I
Aging Dis
. 2018 Oct;
9(5):817-830.
PMID: 30271659
Loss-of-function mutations of progranulin are associated with frontotemporal dementia in humans, and its deficiency in mice is a model for this disease but with normal life expectancy and mild cognitive...
12.
Abbas A, Valek L, Schneider I, Bollmann A, Knopp G, Seitz W, et al.
Environ Sci Pollut Res Int
. 2018 Mar;
25(14):13868-13880.
PMID: 29512011
Anthropogenic micropollutants and transformation products (TPs) negatively affect aquatic ecosystems and water resources. Wastewater treatment plants (WWTP) represent major point sources for (micro)pollutants and TPs in urban water cycles. The...
13.
Torres-Odio S, Key J, Hoepken H, Canet-Pons J, Valek L, Roller B, et al.
J Neuroinflammation
. 2017 Aug;
14(1):154.
PMID: 28768533
Background: PINK1 deficiency causes the autosomal recessive PARK6 variant of Parkinson's disease. PINK1 activates ubiquitin by phosphorylation and cooperates with the downstream ubiquitin ligase PARKIN, to exert quality control and...
14.
Hardt S, Heidler J, Albuquerque B, Valek L, Altmann C, Wilken-Schmitz A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Jul;
1863(11):2727-2745.
PMID: 28720486
Affective and cognitive processing of nociception contributes to the development of chronic pain and vice versa, pain may precipitate psychopathologic symptoms. We hypothesized a higher risk for the latter with...
15.
Valek L, Haussler A, Drose S, Eaton P, Schroder K, Tegeder I
Redox Biol
. 2016 Dec;
11:176-191.
PMID: 27978504
Cyclic GMP-dependent protein kinase 1 (PKG1) mediates presynaptic nociceptive long-term potentiation (LTP) in the spinal cord and contributes to inflammatory pain in rodents but the present study revealed opposite effects...
16.
Valek L, Kanngiesser M, Tegeder I
Data Brief
. 2015 Dec;
5:834-45.
PMID: 26693520
Injury of the sciatic nerve results in regulations of pro- and anti-oxidative enzymes at sites of nociceptive signaling including the injured nerve, dorsal root ganglia (DRGs), dorsal horn of the...
17.
Valek L, Kanngiesser M, Haussler A, Agarwal N, Lillig C, Tegeder I
Free Radic Biol Med
. 2015 Oct;
89:581-92.
PMID: 26456799
Peripheral nerve injury causes redox stress in injured neurons by upregulations of pro-oxidative enzymes, but most neurons survive suggesting an activation of endogenous defense against the imbalance. As potential candidates...