Luciana E S F Machado
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Explore the profile of Luciana E S F Machado including associated specialties, affiliations and a list of published articles.
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10
Citations
97
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Recent Articles
1.
Machado L, Castellen P, Blasios V, Ribeiro-Filho H, Bisson-Filho A, Benites Pariente J, et al.
J Biol Chem
. 2025 Jan;
301(3):108169.
PMID: 39793890
The Min system is a key spatial regulator of cell division in rod-shaped bacteria and the first FtsZ-negative modulator to be recognized. Nevertheless, despite extensive genetic and in vitro studies,...
2.
Durans A, Napoleao-Pego P, Reis F, Dias E, Machado L, Lechuga G, et al.
Vaccines (Basel)
. 2024 Sep;
12(9).
PMID: 39340059
Serological tests are critical tools in the fight against infectious disease. They detect antibodies produced during an adaptive immune response against a pathogen with an immunological reagent, whose antibody binding...
3.
Yang C, Yang C, Tang X, Machado L, Singh J, Peti W, et al.
Free Radic Biol Med
. 2022 Dec;
194:147-159.
PMID: 36462629
Reactive oxygen species (ROS), released as byproducts of mitochondrial metabolism or as products of NADPH oxidases and other processes, can directly oxidize the active-site cysteine (Cys) residue of protein tyrosine...
4.
Mesquita R, Gaviraghi A, Goncalves R, Vannier-Santos M, Mignaco J, Fontes C, et al.
Cells
. 2021 Mar;
10(2).
PMID: 33671793
Flight dispersal represents a key aspect of the evolutionary and ecological success of insects, allowing escape from predators, mating, and colonization of new niches. The huge energy demand posed by...
5.
Machado L, De Paula V, Pustovalova Y, Bezsonova I, Valente A, Korzhnev D, et al.
Biochemistry
. 2018 Sep;
57(40):5797-5806.
PMID: 30207151
Sugar cane defensin 5 (Sd5) is a small antifungal protein, whose structure is held together by four conserved disulfide bridges. Sd5 and other proteins sharing a cysteine-stabilized α-β (CSαβ) fold...
6.
Machado L, Critton D, Page R, Peti W
ACS Omega
. 2017 Dec;
2(11):8313-8318.
PMID: 29214238
SHP2 (Src homology 2 domain-containing protein tyrosine phosphatase 2; PTPN11) is a ubiquitous multidomain, nonreceptor protein tyrosine phosphatase (PTP) that plays an important role in diseases such as cancer, diabetes,...
7.
Machado L, Page R, Peti W
Biomol NMR Assign
. 2017 Sep;
12(1):5-9.
PMID: 28856606
The sequence-specific backbone assignment of hematopoietic protein tyrosine phosphatase (HePTP; PTPN7) in presence of vanadate has been determined, based on triple-resonance experiments using uniformly [C,N]-labeled protein. These assignments facilitate further...
8.
Machado L, Shen T, Page R, Peti W
J Biol Chem
. 2017 Apr;
292(21):8786-8796.
PMID: 28389559
The kinase interaction motif (KIM) family of protein-tyrosine phosphatases (PTPs) includes hematopoietic protein-tyrosine phosphatase (HePTP), striatal-enriched protein-tyrosine phosphatase (STEP), and protein-tyrosine phosphatase receptor type R (PTPRR). KIM-PTPs bind and dephosphorylate...
9.
Choy M, Li Y, Machado L, Kunze M, Connors C, Wei X, et al.
Mol Cell
. 2017 Feb;
65(4):644-658.e5.
PMID: 28212750
Protein function originates from a cooperation of structural rigidity, dynamics at different timescales, and allostery. However, how these three pillars of protein function are integrated is still only poorly understood....
10.
Cruzeiro-Silva C, Gomes-Neto F, Machado L, Miyamoto C, Pinheiro A, Correa-Pereira N, et al.
Biochemistry
. 2014 Apr;
53(18):2890-902.
PMID: 24738963
One of the ancestral features of thioredoxins is the presence of a water cavity. Here, we report that a largely hydrated, conserved, buried aspartic acid in the water cavity modulates...