Lucia Demkova
Overview
Explore the profile of Lucia Demkova including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
137
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Recent Articles
1.
Demkova L, Matuskova M, Gercakova K, Kozovska Z, Smolkova B, Kucerova L
Neoplasma
. 2024 Nov;
71(5):417-427.
PMID: 39556431
The aberrant activation of the hepatocyte growth factor receptor (c-Met) in malignant melanoma is associated with poor prognosis, fostering tumor progression, angiogenesis, and invasiveness. While therapeutic targeting of this pathway...
2.
Jakubechova J, Smolkova B, Furdova A, Demkova L, Altanerova U, Nicodemou A, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37629139
Extracellular vesicles secreted from uveal melanoma (UM) cells are involved in the establishment of the premetastatic niche and display transforming potential for the formation of metastases, preferentially in the liver....
3.
Soltysova A, Dvorska D, Kajabova V, Pecimonova M, Cepcekova K, Ficek A, et al.
Clin Transl Med
. 2023 Jul;
13(7):e1317.
PMID: 37478301
No abstract available.
4.
Buocikova V, Tyciakova S, Pilalis E, Mastrokalou C, Urbanova M, Matuskova M, et al.
Front Pharmacol
. 2022 Oct;
13:991751.
PMID: 36278182
Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors. Although epigenome modulation provides a promising avenue...
5.
Radaszkiewicz T, Noskova M, Gomoryova K, Vondalova Blanarova O, Radaszkiewicz K, Pickova M, et al.
Elife
. 2021 Oct;
10.
PMID: 34702444
RNF43 is an E3 ubiquitin ligase and known negative regulator of WNT/β-catenin signaling. We demonstrate that RNF43 is also a regulator of noncanonical WNT5A-induced signaling in human cells. Analysis of...
6.
Kajabova V, Soltysova A, Demkova L, Plesnikova P, Lyskova D, Furdova A, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34639089
Uveal melanoma (UM) is an ocular tumor with a dismal prognosis. Despite the availability of precise molecular and cytogenetic techniques, clinicopathologic features with limited accuracy are widely used to predict...
7.
Soltysova A, Sedlackova T, Dvorska D, Jasek K, Chokhachi Baradaran P, Kajabova V, et al.
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33348918
Despite outstanding advances in diagnosis and the treatment of primary uveal melanoma (UM), nearly 50% of UM patients develop metastases via hematogenous dissemination, driven by the epithelial-mesenchymal transition (EMT). Despite...
8.
Demkova L, Kucerova L
Mol Cancer
. 2018 Feb;
17(1):26.
PMID: 29455657
Metastatic disease in a cancer patient still remains a therapeutic challenge. Metastatic process involves many steps, during which malignant cells succeed to activate cellular pathways promoting survival in hostile environment,...
9.
Kucerova L, Demkova L, Skolekova S, Bohovic R, Matuskova M
BMC Cancer
. 2016 May;
16:308.
PMID: 27175734
Background: Small molecule inhibitor of tyrosine kinase activity, compound SU11274, was reported to have antitumorigenic and antimetastatic effect in melanoma. In this study, we evaluated, whether similar effect could be...
10.
Skolekova S, Matuskova M, Bohac M, Toro L, Durinikova E, Tyciakova S, et al.
Cell Commun Signal
. 2016 Feb;
14:7.
PMID: 26915660
No abstract available.