Lucas Tortorelli
Overview
Explore the profile of Lucas Tortorelli including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
186
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0
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Recent Articles
1.
Denver P, Tortorelli L, Hov K, Berg J, Giil L, Nazmi A, et al.
Brain Behav Immun Health
. 2025 Jan;
43():100920.
PMID: 39839987
Delirium is a highly prevalent neuropsychiatric syndrome characterised by acute and fluctuating impairments in attention and cognition. Mechanisms driving delirium are poorly understood but it has been suggested that blood...
2.
Healy D, Murray C, McAdams C, Power R, Hollier P, Lambe J, et al.
Commun Biol
. 2024 Jan;
7(1):105.
PMID: 38228820
Age is a significant but heterogeneous risk factor for acute neuropsychiatric disturbances such as delirium. Neuroinflammation increases with aging but the determinants of underlying risk for acute dysfunction upon systemic...
3.
McGarry N, Murray C, Garvey S, Wilkinson A, Tortorelli L, Ryan L, et al.
Brain Behav Immun
. 2021 Apr;
95:413-428.
PMID: 33892139
Double stranded RNA is generated during viral replication. The synthetic analogue poly I:C is frequently used to mimic anti-viral innate immune responses in models of psychiatric and neurodegenerative disorders including...
4.
McGarry N, Murray C, Garvey S, Wilkinson A, Tortorelli L, Ryan L, et al.
bioRxiv
. 2021 Jan;
PMID: 33442686
Double stranded RNA is generated during viral replication. The synthetic analog poly I:C is frequently used to mimic anti-viral innate immune responses in models of psychiatric and neurodegenerative disease including...
5.
Skelly D, Griffin E, Murray C, Harney S, OBoyle C, Hennessy E, et al.
Mol Psychiatry
. 2019 Mar;
24(10):1566.
PMID: 30890763
Following publication of this article, the authors noticed an error in the abstract, where they incorrectly stated that: "Direct application of IL-1β to ex vivo hippocampal slices induced non-synaptic depolarisation...
6.
Nazmi A, Field R, Griffin E, Haugh O, Hennessy E, Cox D, et al.
Glia
. 2019 Jan;
67(7):1254-1276.
PMID: 30680794
Type I interferons (IFN-I) are the principal antiviral molecules of the innate immune system and can be made by most cell types, including central nervous system cells. IFN-I has been...
7.
da Cruz Fernandes M, Severino A, Zago A, Tortorelli L, Carvalho F, Schneider F
J Trace Elem Med Biol
. 2018 Jun;
49:128-133.
PMID: 29895361
The role of the choroid plexus (CP) in iron (Fe) homeostasis has been suggested as the main mechanism of Fe uptake and storage in the mammalian central nervous system. Thus,...
8.
Skelly D, Griffin E, Murray C, Harney S, OBoyle C, Hennessy E, et al.
Mol Psychiatry
. 2018 Jun;
24(10):1533-1548.
PMID: 29875474
Systemic inflammation can impair cognition with relevance to dementia, delirium and post-operative cognitive dysfunction. Episodes of delirium also contribute to rates of long-term cognitive decline, implying that these acute events...
9.
Tramontina A, Nardin P, Quincozes-Santos A, Tortorelli L, Wartchow K, Andreazza A, et al.
Neurochem Res
. 2012 Feb;
37(7):1399-408.
PMID: 22359053
Diabetes mellitus is a disease associated with several changes in the central nervous system, including oxidative stress and abnormal glutamatergic neurotransmission, and the astrocytes play an essential role in these...
10.
Nardin P, Tortorelli L, Quincozes-Santos A, De Almeida L, Leite M, Thomazi A, et al.
Neurochem Res
. 2009 Mar;
34(9):1603-11.
PMID: 19288274
Hippocampal slices have been widely used to investigate electrophysiological and metabolic neuronal parameters, as well as parameters of astroglial activity including protein phosphorylation and glutamate uptake. S100B is an astroglial-derived...