Lucas C Pantaleao
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Explore the profile of Lucas C Pantaleao including associated specialties, affiliations and a list of published articles.
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19
Citations
226
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Recent Articles
1.
Sandovici I, Fernandez-Twinn D, Campbell N, Cooper W, Sekita Y, Zvetkova I, et al.
Cell Rep
. 2024 Sep;
43(9):114750.
PMID: 39283743
Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Its expression is dysregulated in a number of human diseases, including metabolic disorders and...
2.
Dearden L, Furigo I, Pantaleao L, Wong L, Fernandez-Twinn D, de Almeida-Faria J, et al.
PLoS Biol
. 2024 Jun;
22(6):e3002641.
PMID: 38833481
In utero exposure to maternal obesity programs increased obesity risk. Animal models show that programmed offspring obesity is preceded by hyperphagia, but the mechanisms that mediate these changes are unknown....
3.
Pantaleao L, Loche E, Fernandez-Twinn D, Dearden L, Cordova-Casanova A, Osmond C, et al.
Mol Metab
. 2024 Jan;
80:101875.
PMID: 38218535
Objective: We investigated the potential involvement of miRNAs in the developmental programming of cardiovascular diseases (CVD) by maternal obesity. Methods: Serum miRNAs were measured in individuals from the Helsinki Birth...
4.
Tarry-Adkins J, Robinson I, Pantaleao L, Armstrong J, Thackray B, Holzner L, et al.
Diabetologia
. 2023 Sep;
66(12):2320-2331.
PMID: 37670017
Aims/hypothesis: Metformin is increasingly used therapeutically during pregnancy worldwide, particularly in the treatment of gestational diabetes, which affects a substantial proportion of pregnant women globally. However, the impact on placental...
5.
Kaisinger L, Kentistou K, Stankovic S, Gardner E, Day F, Zhao Y, et al.
Cell Genom
. 2023 Aug;
3(8):100362.
PMID: 37601970
Obesity contributes substantially to the global burden of disease and has a significant heritable component. Recent large-scale exome sequencing studies identified several genes in which rare, protein-coding variants have large...
6.
Schoonejans J, Blackmore H, Ashmore T, Pantaleao L, Pisani L, Dearden L, et al.
Diabetologia
. 2022 Sep;
65(12):2132-2145.
PMID: 36112170
Aims/hypothesis: Metformin is increasingly used to treat gestational diabetes (GDM) and pregnancies complicated by pregestational type 2 diabetes or polycystic ovary syndrome but data regarding long-term offspring outcome are lacking...
7.
Pantaleao L, Inzani I, Furse S, Loche E, Hufnagel A, Ashmore T, et al.
Elife
. 2022 Jan;
11.
PMID: 35025731
Maternal obesity during pregnancy has immediate and long-term detrimental effects on the offspring heart. In this study, we characterized the cardiac and circulatory lipid profiles in late gestation E18.5 fetuses...
8.
Mennitti L, Carpenter A, Loche E, Pantaleao L, Fernandez-Twinn D, Schoonejans J, et al.
Int J Obes (Lond)
. 2021 Oct;
46(2):269-278.
PMID: 34663892
Objective: This study investigated the effect of maternal obesity on aged-male offspring liver phenotype and hepatic expression of a programmed miRNA. Methods: A mouse model (C57BL/6 J) of maternal diet-induced...
9.
Perez-Sanchez C, Barbarroja N, Pantaleao L, Lopez-Sanchez L, Ozanne S, Jurado-Gamez B, et al.
J Pers Med
. 2021 Feb;
11(2).
PMID: 33572343
This study represents a novel proof of concept of the clinical utility of miRNAs from exhaled breath condensate (EBC) as biomarkers of lung cancer (LC). Genome-wide miRNA profiling and machine...
10.
de Almeida-Faria J, Duque-Guimaraes D, Ong T, Pantaleao L, Carpenter A, Loche E, et al.
Diabetologia
. 2021 Jan;
64(4):890-902.
PMID: 33501603
Aims/hypothesis: Levels of the microRNA (miRNA) miR-126-3p are programmed cell-autonomously in visceral adipose tissue of adult offspring born to obese female C57BL/6J mice. The spectrum of miR-126-3p targets and thus...