Lucas Abreu Diniz
Overview
Explore the profile of Lucas Abreu Diniz including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
6
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0
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Recent Articles
1.
Sheu-Idrees R, Marques G, Santana P, Diniz L, Resende D, Odoma S, et al.
Mem Inst Oswaldo Cruz
. 2025 Feb;
120:e240161.
PMID: 39936703
Background: Chagas disease (CD) is a neglected tropical disease caused by Trypanosoma cruzi. The current drugs used to treat these diseases have limited efficacy and produce severe side effects. 4-aminoquinoline...
2.
Cerutti J, Diniz L, Correa Santos V, Vilchez Larrea S, Alonso G, Ferreira R, et al.
ACS Med Chem Lett
. 2025 Jan;
16(1):72-79.
PMID: 39811116
Cruzipain (CZP) is an essential cysteine protease of , the etiological agent of Chagas disease, and a promising druggable target. To date, no CZP inhibitors have reached clinical use, with...
3.
Cerutti J, Diniz L, Correa Santos V, Vilchez Larrea S, Alonso G, Ferreira R, et al.
Molecules
. 2024 Sep;
29(17).
PMID: 39275072
Cruzipain (CZP), the major cysteine protease present in , the ethiological agent of Chagas disease, has attracted particular attention as a therapeutic target for the development of targeted covalent inhibitors...
4.
Fernandes Melo Reis R, Dos Santos E, Benedetti M, Reis A, Brandao G, Silva G, et al.
Eur J Med Chem
. 2023 Jul;
258:115622.
PMID: 37441850
Chagas disease (CD) is a neglected tropical disease endemic in 21 countries and affects about 8 million people around the world. The pharmacotherapy for this disease is limited to two...
5.
do Valle Moreira T, Martins L, Diniz L, Bernardes T, de Oliveira R, Ferreira R
Pathogens
. 2023 Feb;
12(2).
PMID: 36839523
Chagas disease and Human African Trypanosomiasis, caused by and , respectively, pose relevant health challenges throughout the world, placing 65 to 70 million people at risk each. Given the limited...