Lucas A D Nicolau
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Explore the profile of Lucas A D Nicolau including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
132
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Recent Articles
1.
Pereira-Silva G, Cornelio C, Pacheco G, Rochael N, Gomes I, Cajado A, et al.
Life Sci
. 2024 Jul;
352:122895.
PMID: 38986896
Aims: To investigate the SARS-CoV-2 Spike protein (Spk)-induced inflammatory response and its downmodulation by diminazene aceturate (DIZE). Materials And Methods: Through inducing Spk inflammation in murine models, leukocyte migration to...
2.
Chaves L, Oliveira A, Pinho S, Sousa G, Oliveira A, Lopes A, et al.
Int J Biol Macromol
. 2024 Jan;
260(Pt 1):129397.
PMID: 38219933
Biotechnological advancements require the physicochemical alteration of molecules to enhance their biological efficacy for the effective treatment of gastric ulcers. The study aimed to produce a polyelectrolytic compound from red...
3.
Sales T, Sidou F, da Costa Filho H, Nogueira K, Dias Junior G, de Sousa Lima M, et al.
Laryngoscope
. 2024 Jan;
134(7):3080-3085.
PMID: 38214310
Objective: This study aimed to evaluate the role of pepsin inhibitors in the inflammatory response and their effects on laryngeal mucosal integrity during gastroesophageal reflux (GERD) under in vivo conditions....
4.
Santos E, Silva P, Sousa P, Aquino C, Pacheco G, Teixeira L, et al.
Chem Biol Interact
. 2022 Sep;
367:110161.
PMID: 36116513
Diminazene aceturate (DIZE), an antiparasitic, is an ACE2 activator, and studies show that activators of this enzyme may be beneficial for COVID-19, disease caused by SARS-CoV-2. Thus, the objective was...
5.
Sousa F, Pacheco G, Oliveira A, Nicolau L, Lopes A, Ferreira-Fernandes H, et al.
Life Sci
. 2021 Aug;
284:119869.
PMID: 34358552
Aims: Investigate the involvement of Hydrogen sulfide (HS) in inflammatory parameters and intestinal morphology caused by cholera toxin (CT) in mice. Main Methods: Mice were subjected to the procedure of...
6.
Nicolau L, Noleto I, Medeiros J
Expert Rev Clin Pharmacol
. 2020 Jul;
13(8):807-811.
PMID: 32686527
No abstract available.
7.
Nicolau L, Magalhaes P, Vale M
Med Hypotheses
. 2020 Jun;
143:109886.
PMID: 32504925
Coronavirus disease 2019 (COVID-19) is an infectious disease with fast spreading all over the world caused by the SARS-CoV-2 virus which can culminate in a severe acute respiratory syndrome by...
8.
Laryngeal Mucosa Alterations in Mice Model of Gastroesophageal Reflux: Effects of Topical Protection
Figueiredo A, Sales T, Nicolau L, Nunes A, Costa-Filho H, Moreira R, et al.
Laryngoscope
. 2020 Mar;
130(12):E889-E895.
PMID: 32159864
Objectives/hypothesis: The objectives of this study were to evaluate laryngeal inflammation and mucosal integrity in a murine model of reflux disease and to assess the protective effects of topical agents...
9.
Araujo T, de Oliveira T, de Sousa N, Souza L, Sousa F, de Oliveira A, et al.
Pharmaceuticals (Basel)
. 2020 Jan;
13(1).
PMID: 31963683
var. cebil (Griseb.) Altschul (Fabaceae family), commonly known as the red angico tree, is a medicinal plant found throughout Brazil's semi-arid area. In this study, a chemical analysis was performed...
10.
Nicolau L, Batista-Lima F, Santana A, Sales T, Carmo-Neto J, Freitas G, et al.
Carbohydr Polym
. 2019 Oct;
226:115205.
PMID: 31582062
This study aimed to investigate a standardized biopolymer, cashew gum (CG), in human oesophageal mucosa and mice with experimentally-induced non-erosive reflux disease (NERD). Human oesophageal biopsies from NERD patients were...