Luca Peruzzotti-Jametti
Overview
Explore the profile of Luca Peruzzotti-Jametti including associated specialties, affiliations and a list of published articles.
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61
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1411
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Recent Articles
1.
Mozafari S, Peruzzotti-Jametti L, Pluchino S
J Cereb Blood Flow Metab
. 2025 Mar;
:271678X251325805.
PMID: 40079508
Demyelination is a common feature of neuroinflammatory and degenerative diseases of the central nervous system (CNS), such as multiple sclerosis (MS). It is often linked to disruptions in intercellular communication,...
2.
Vecchiarelli H, Bisht K, Sharma K, Novak S, Traetta M, Garcia-Segura M, et al.
bioRxiv
. 2024 Oct;
PMID: 39463930
This study examined dark microglia-a state linked to central nervous system pathology and neurodegeneration-during postnatal development in the mouse ventral hippocampus, finding that dark microglia interact with blood vessels and...
3.
Ionescu R, Nicaise A, Reisz J, Williams E, Prasad P, Willis C, et al.
Cell Stem Cell
. 2024 Oct;
31(11):1574-1590.e11.
PMID: 39437792
Senescent neural progenitor cells have been identified in brain lesions of people with progressive multiple sclerosis (PMS). However, their role in disease pathobiology and contribution to the lesion environment remains...
4.
Garcia-Segura M, Pluchino S, Peruzzotti-Jametti L
Adv Neurobiol
. 2024 Aug;
37:607-622.
PMID: 39207716
Microglia, immune sentinels of the central nervous system (CNS), play a critical role in maintaining its health and integrity. This chapter delves into the concept of immunometabolism, exploring how microglial...
5.
Yao X, Chen J, Garcia-Segura M, Wen Z, Yu Z, Huang Z, et al.
Exp Neurol
. 2024 Aug;
380:114909.
PMID: 39097074
Functional and pathological recovery after spinal cord injury (SCI) is often incomplete due to the limited regenerative capacity of the central nervous system (CNS), which is further impaired by several...
6.
Totsch S, Ishizuka A, Kang K, Gary S, Rocco A, Fan A, et al.
Mol Cancer Ther
. 2024 May;
23(9):1273-1281.
PMID: 38710101
Oncolytic virotherapy or immunovirotherapy is a strategy that utilizes viruses to selectively infect and kill tumor cells while also stimulating an immune response against the tumor. Early clinical trials in...
7.
Leone M, Gelati M, Profico D, Gobbi C, Pravata E, Copetti M, et al.
Cell Stem Cell
. 2023 Nov;
30(12):1597-1609.e8.
PMID: 38016468
We report the analysis of 1 year of data from the first cohort of 15 patients enrolled in an open-label, first-in-human, dose-escalation phase I study (ClinicalTrials.gov: NCT03282760, EudraCT2015-004855-37) to determine...
8.
Hermann D, Peruzzotti-Jametti L, Giebel B, Pluchino S
Brain
. 2023 Sep;
147(2):372-389.
PMID: 37768167
Extracellular vesicles (EVs) are extremely versatile naturally occurring membrane particles that convey complex signals between cells. EVs of different cellular sources are capable of inducing striking therapeutic responses in neurological...
9.
Hermann D, Bacigaluppi M, Peruzzotti-Jametti L
Front Cell Neurosci
. 2023 Sep;
17:1269763.
PMID: 37731464
No abstract available.
10.
Hamel R, Peruzzotti-Jametti L, Ridley K, Testa V, Yu B, Rowitch D, et al.
Heliyon
. 2023 Aug;
9(8):e18339.
PMID: 37636454
Traumatic spinal cord injuries (SCI) are a group of highly debilitating pathologies affecting thousands annually, and adversely affecting quality of life. Currently, no fully restorative therapies exist, and SCI still...