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Luca Cavinato

Explore the profile of Luca Cavinato including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 113
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Recent Articles
1.
Cavinato L, Luly F, Pastore V, Chiappetta D, Sangiorgi G, Ferrara E, et al.
Eur Respir J . 2022 Dec; 61(4). PMID: 36455959
Background: Cystic fibrosis (CF), which is caused by mutations in the CF transmembrane conductance regulator (CFTR), is characterised by chronic bacterial lung infection and inflammation. In CF, monocytes and monocyte-derived...
2.
Mecocci S, Gevi F, Pietrucci D, Cavinato L, Luly F, Pascucci L, et al.
Nutrients . 2020 Sep; 12(10). PMID: 32977543
In recent years, extracellular vesicles (EVs), cell-derived micro and nano-sized structures enclosed in a double-layer membrane, have been in the spotlight for their high potential in diagnostic and therapeutic applications....
3.
Quaglio D, Mangoni M, Stefanelli R, Corradi S, Casciaro B, Vergine V, et al.
J Org Chem . 2020 Aug; 85(16):10891-10901. PMID: 32806095
Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural -beyerene diterpene was identified as a promising inhibitor of the enzyme responsible for...
4.
Ghirga F, Stefanelli R, Cavinato L, Lo Sciuto A, Corradi S, Quaglio D, et al.
J Antimicrob Chemother . 2020 Jun; 75(9):2564-2572. PMID: 32514531
Background: Colistin is a last-resort treatment option for many MDR Gram-negative bacteria. The covalent addition of l-aminoarabinose to the lipid A moiety of LPS is the main colistin resistance mechanism...
5.
Cavinato L, Genise E, Luly F, Di Domenico E, Del Porto P, Ascenzioni F
Front Microbiol . 2020 Mar; 11:326. PMID: 32210934
Reactive oxygen species (ROS) are small oxygen-derived molecules that are used to control infections by phagocytic cells. In macrophages, the oxidative burst produced by the NOX2 NADPH-oxidase is essential to...
6.
Luly F, Leveque M, Licursi V, Cimino G, Martin-Chouly C, Theret N, et al.
Sci Rep . 2019 Nov; 9(1):16259. PMID: 31700158
Cystic fibrosis (CF) is an inherited disease that is characterised by susceptibility to bacterial infections and chronic lung inflammation. Recently, it was suggested that macrophages contribute to impaired host defence...
7.
De Rocco D, Pompili B, Castellani S, Morini E, Cavinato L, Cimino G, et al.
Int J Mol Sci . 2018 Apr; 19(4). PMID: 29673202
Improving the efficacy of gene therapy vectors is still an important goal toward the development of safe and efficient gene therapy treatments. S/MAR (scaffold/matrix attached region)-based vectors are maintained extra-chromosomally...