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Luc St-Onge

Explore the profile of Luc St-Onge including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 249
Followers 0
Related Specialties
Biology
Cell Biology
Molecular Biology
Top 10 Co-Authors
Benoit R Gauthier
Domenico Bosco
Anna M Wobus
Piero Marchetti
Przemyslaw Blyszczuk
Gabriela Kania
Nadia Cobo-Vuilleumier
Mathurin Baquie
Petra I Lorenzo
Claes B Wollheim
Published In
Hum Mol Genet
Proc Natl Acad Sci U S A
Stem Cells
J Cell Biol
Int J Dev Biol
Affiliations
Soon will be listed here.
Recent Articles
1.
LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus
Cobo-Vuilleumier N, Lorenzo P, Rodriguez N, Herrera Gomez I, Fuente-Martin E, Lopez-Noriega L, et al.
Nat Commun . 2018 Apr; 9(1):1488. PMID: 29662071
Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell...
2.
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects β-cells against stress-induced apoptosis
Baquie M, St-Onge L, Kerr-Conte J, Cobo-Vuilleumier N, Lorenzo P, Jimenez Moreno C, et al.
Hum Mol Genet . 2017 Nov; 27(2):406. PMID: 29186426
No abstract available.
3.
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis
Baquie M, St-Onge L, Kerr-Conte J, Cobo-Vuilleumier N, Lorenzo P, Jimenez Moreno C, et al.
Hum Mol Genet . 2011 May; 20(14):2823-33. PMID: 21536586
Liver receptor homolog (LRH-1) is an orphan nuclear receptor (NR5A2) that regulates cholesterol homeostasis and cell plasticity in endodermal-derived tissues. Estrogen increases LRH-1 expression conveying cell protection and proliferation. Independently,...
4.
Signals from embryonic fibroblasts induce adult intestinal epithelial cells to form nestin-positive cells with proliferation and multilineage differentiation capacity in vitro
Wiese C, Rolletschek A, Kania G, Navarrete-Santos A, Anisimov S, Steinfarz B, et al.
Stem Cells . 2006 Jun; 24(9):2085-97. PMID: 16741226
The intestinal epithelium has one of the greatest regenerative capacities in the body; however, neither stem nor progenitor cells have been successfully cultivated from the intestine. In this study, we...
5.
Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells
Blyszczuk P, Asbrand C, Rozzo A, Kania G, St-Onge L, Rupnik M, et al.
Int J Dev Biol . 2004 Dec; 48(10):1095-104. PMID: 15602695
We present a new strategy for the differentiation of embryonic stem (ES) cells into insulin-producing cells via a multi-step process without selection and induction of nestin-positive cells. During ES cell...
6.
The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets
Brun T, Franklin I, St-Onge L, Biason-Lauber A, Schoenle E, Wollheim C, et al.
J Cell Biol . 2004 Dec; 167(6):1123-35. PMID: 15596543
The mechanism by which the beta-cell transcription factor Pax4 influences cell function/mass was studied in rat and human islets of Langerhans. Pax4 transcripts were detected in adult rat islets, and...
7.
Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells
Blyszczuk P, Czyz J, Kania G, Wagner M, Roll U, St-Onge L, et al.
Proc Natl Acad Sci U S A . 2003 Jan; 100(3):998-1003. PMID: 12525695
Mouse embryonic stem (ES) cells differentiate into cells of all three primary germ layers including endodermal cells that produce insulin in vitro. We show that constitutive expression of Pax4 (Pax4(+)),...