Lourens J D Zaneveld
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Explore the profile of Lourens J D Zaneveld including associated specialties, affiliations and a list of published articles.
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14
Citations
240
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Recent Articles
1.
Chang T, Teleshova N, Rapista A, Paluch M, Anderson R, Waller D, et al.
FEBS Lett
. 2007 Sep;
581(24):4596-602.
PMID: 17825297
SAMMA, a mandelic acid condensation polymer, exhibits a broad antimicrobial activity against several sexually transmitted pathogens including human immunodeficiency virus (HIV). Here we demonstrated that SAMMA suppressed HIV transmission by...
2.
Anderson R, Feathergill K, Waller D, Zaneveld L
J Androl
. 2006 Apr;
27(4):568-77.
PMID: 16582417
SAMMA is licensed for development as a contraceptive microbicide. Understanding mechanisms of its biological activity is prerequisite to designing more active second generation products. This study examined Ca(2+) involvement in...
3.
Simoes J, Bahamondes L, Camargo R, Alves V, Zaneveld L, Waller D, et al.
Br J Clin Pharmacol
. 2006 Jan;
61(2):211-7.
PMID: 16433875
Aim: To compare the effectiveness of an acid-buffering formulation gel (ACIDFORM) with metronidazole gel in the treatment of symptomatic bacterial vaginosis (BV). Methods: After a confirmed diagnosis of BV according...
4.
Garg S, Vermani K, Garg A, Anderson R, Rencher W, Zaneveld L
Pharm Res
. 2005 Apr;
22(4):584-95.
PMID: 15846466
Purpose: Polystyrene sulfonate (PSS) is a novel noncytotoxic antimicrobial contraceptive agent. A gel formulation of PSS was found safe for vaginal administration in phase I clinical trials. The purpose of...
5.
Anderson R, Feathergill K, Diao X, Chany 2nd C, Rencher W, Zaneveld L, et al.
Contraception
. 2004 Oct;
70(5):415-22.
PMID: 15504382
This study evaluated contraception by formulated Ushercell, a uniquely high-molecular-weight form of cellulose sulfate, in the rabbit. Variables included (1) dose effectiveness, (2) duration of effectiveness, and (3) formulation excipients....
6.
Cheshenko N, Keller M, MasCasullo V, Jarvis G, Cheng H, John M, et al.
Antimicrob Agents Chemother
. 2004 May;
48(6):2025-36.
PMID: 15155195
Topical microbicides designed to prevent acquisition of sexually transmitted infections are urgently needed. Nonoxynol-9, the only commercially available spermicide, damages epithelium and may enhance human immunodeficiency virus transmission. The observation...
7.
Garg S, Tambwekar K, Vermani K, Kandarapu R, Garg A, Waller D, et al.
AIDS Patient Care STDS
. 2003 Sep;
17(8):377-99.
PMID: 13678540
In recent years, AIDS and sexually transmitted diseases (STDs) have become a burgeoning problem and are spreading at an alarming rate. Microbicides are being developed as a new therapeutic category...
8.
Hardy E, de Padua K, Hebling E, Osis M, Zaneveld L
Contraception
. 2003 May;
67(5):391-5.
PMID: 12742563
The rapid spread of HIV/AIDS in the female population increases the urgency of developing new formulations that offer protection from this disease as well as other sexually transmitted infections. In...
9.
Garg S, Kandarapu R, Vermani K, Tambwekar K, Garg A, Waller D, et al.
AIDS Patient Care STDS
. 2003 Mar;
17(1):17-32.
PMID: 12614517
Microbicides, the compounds and formulations that can prevent transmission of sexually transmitted diseases (STDs)/HIV are being pursued actively as a promising AIDS intervention. The drug development chain for a topical...
10.
Vermani K, Garg S, Zaneveld L
Drug Dev Ind Pharm
. 2002 Nov;
28(9):1133-46.
PMID: 12455472
The vaginal route of administration offers a promising option for local and systemic delivery of drugs. Conventional vaginal formulations are associated with limitations of poor retention, leakage, and messiness, thereby...