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Louise Bird

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Articles 13
Citations 118
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Recent Articles
1.
Ford A, Breitgoff F, Pasquini M, MacKenzie A, McElroy S, Baker S, et al.
Patterns (N Y) . 2023 May; 4(5):100733. PMID: 37223265
Understanding a drug candidate's mechanism of action is crucial for its further development. However, kinetic schemes are often complex and multi-parametric, especially for proteins in oligomerization equilibria. Here, we demonstrate...
2.
Shepherd C, Robinson S, Berizzi A, Thompson L, Bird L, Culurgioni S, et al.
ACS Med Chem Lett . 2022 Jul; 13(7):1172-1181. PMID: 35859869
Surface plasmon resonance (SPR) is a widely used method to study ligand-protein interactions. The throughput and sensitivity of SPR has made it an important technology for measuring low-affinity, ultralow weight...
3.
Caissie A, Olson R, Barbera L, ODonnell J, Davis C, Croke J, et al.
Curr Oncol . 2022 May; 29(5):3698-3707. PMID: 35621686
Despite the known importance and necessity of the standardized collection and use of patient-reported outcomes (PROs), there remain challenges to successful clinical implementation. Facilitated through a quality improvement initiative spearheaded...
4.
Atwood T, Lamichhane N, Howell K, Weiss S, Bird L, Pearson C, et al.
J Appl Clin Med Phys . 2022 Feb; 23(6):e13559. PMID: 35170198
No abstract available.
5.
Faheem M, Valadares N, Brandao-Neto J, Bellini D, Collins P, Pearce N, et al.
Biochem J . 2021 Sep; 478(19):3655-3670. PMID: 34529035
Several Schistosoma species cause Schistosomiasis, an endemic disease in 78 countries that is ranked second amongst the parasitic diseases in terms of its socioeconomic impact and human health importance. The...
6.
Robin G, Brown E, Davis C, Bird L, Wilson L, Halperin R, et al.
J Cancer Educ . 2021 Sep; 37(6):1834-1841. PMID: 34518991
Patient engagement and education have been mandated across Canadian radiation oncology programs (ROP). Guidance documents include the 2014 Canadian Association of Radiation Oncology (CARO) Radiation Therapy Patient Charter, the 2016...
7.
Rodzli N, Lockhart-Cairns M, Levy C, Chipperfield J, Bird L, Baldock C, et al.
Biophys J . 2020 Jul; 119(3):667-689. PMID: 32652058
PSD-95 is a member of the membrane-associated guanylate kinase class of proteins that forms scaffolding interactions with partner proteins, including ion and receptor channels. PSD-95 is directly implicated in modulating...
8.
Torini J, Romanello L, Batista F, Balasco Serrao V, Faheem M, Zeraik A, et al.
PLoS One . 2018 Sep; 13(9):e0203532. PMID: 30192840
Purine nucleoside phosphorylases (PNPs) play an important role in the blood fluke parasite Schistosoma mansoni as a key enzyme of the purine salvage pathway. Here we present the structural and...
9.
Asiani K, Williams H, Bird L, Jenner M, Searle M, Hobman J, et al.
Mol Microbiol . 2016 Apr; 101(5):731-42. PMID: 27085056
Ag(+) resistance was initially found on the Salmonella enetrica serovar Typhimurium multi-resistance plasmid pMG101 from burns patients in 1975. The putative model of Ag(+) resistance, encoded by the sil operon...
10.
Hu N, Rada H, Rahman N, Nettleship J, Bird L, Iwata S, et al.
Methods Mol Biol . 2014 Dec; 1261:197-209. PMID: 25502201
A key step in the production of recombinant membrane proteins for structural studies is the optimization of protein yield and quality. One commonly used approach is to fuse the protein...