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Louise Aas Holm

Explore the profile of Louise Aas Holm including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 78
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Recent Articles
1.
Chami N, Wang Z, Svenstrup V, Diez-Obrero V, Obrero V, Hemerich D, et al.
medRxiv . 2025 Mar; PMID: 40061343
Obesity is a highly heterogeneous disease that cannot be captured by one single adiposity trait. Here, we performed a multi-trait analysis to study obesity in the context of its common...
2.
Niu L, Stinson S, Holm L, Lund M, Fonvig C, Cobuccio L, et al.
Nat Genet . 2025 Feb; 57(3):635-646. PMID: 39972214
Our current understanding of the determinants of plasma proteome variation during pediatric development remains incomplete. Here, we show that genetic variants, age, sex and body mass index significantly influence this...
3.
Pedersen R, Fraulund M, Chabanova E, Holm L, Hansen T, Thomsen H, et al.
Child Obes . 2025 Jan; PMID: 39841082
Steatotic liver disease (SLD) represents a multisystem disease and is a common complication of childhood obesity. We studied fat content at the abdominal level (liver, subcutaneous, and visceral) and the...
4.
Huang Y, Stinson S, Thodberg M, Holm L, Thielemann R, Sulek K, et al.
EBioMedicine . 2025 Jan; 112:105537. PMID: 39753034
Background: Lipid species are emerging as biomarkers for cardiometabolic risk in both adults and children. The genetic regulation of lipid species and their impact on cardiometabolic risk during early life...
5.
Byberg S, Holt J, Sandsdal R, Holm L, Madsen L, Christensen B, et al.
BMJ Open . 2024 Nov; 14(11):e082446. PMID: 39551589
Introduction: Childhood-onset obesity poses significant health risks, including early-onset type 2 diabetes, cardiovascular disease, and reduced quality of life. Hospital-based non-pharmacological obesity care can reduce childhood obesity, but 25% of...
6.
Nishijima S, Stankevic E, Aasmets O, Schmidt T, Nagata N, Keller M, et al.
Cell . 2024 Nov; 188(1):222-236.e15. PMID: 39541968
The microbiota in individual habitats differ in both relative composition and absolute abundance. While sequencing approaches determine the relative abundances of taxa and genes, they do not provide information on...
7.
Huang Y, Sulek K, Stinson S, Holm L, Kim M, Trost K, et al.
Nat Med . 2024 Sep; 31(1):294-305. PMID: 39304782
Pediatric obesity is a progressive, chronic disease that can lead to serious cardiometabolic complications. Here we investigated the peripheral lipidome in 958 children and adolescents with overweight or obesity and...
8.
Stinson S, Kromann Reim P, Lund M, Lausten-Thomsen U, Holm L, Huang Y, et al.
EBioMedicine . 2024 Jun; 105:105205. PMID: 38918147
Background: Birth weight (BW) is associated with risk of cardiometabolic disease (CMD) in adulthood, which may depend on the state of obesity, in particular if developed at a young age....
9.
Bradfeld J, Kember R, Ulrich A, Balkhiyarova Z, Alyass A, Aris I, et al.
Genome Biol . 2024 May; 25(1):129. PMID: 38773652
No abstract available.
10.
Bradfield J, Kember R, Ulrich A, Balkhiyarova Z, Alyass A, Aris I, et al.
Genome Biol . 2024 Jan; 25(1):22. PMID: 38229171
Background: Pubertal growth patterns correlate with future health outcomes. However, the genetic mechanisms mediating growth trajectories remain largely unknown. Here, we modeled longitudinal height growth with Super-Imposition by Translation And...