Louis-Felix Nothias
Overview
Explore the profile of Louis-Felix Nothias including associated specialties, affiliations and a list of published articles.
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54
Citations
4370
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Recent Articles
1.
Heuckeroth S, Damiani T, Smirnov A, Mokshyna O, Brungs C, Korf A, et al.
Nat Protoc
. 2024 May;
19(9):2597-2641.
PMID: 38769143
Untargeted mass spectrometry (MS) experiments produce complex, multidimensional data that are practically impossible to investigate manually. For this reason, computational pipelines are needed to extract relevant information from raw spectral...
2.
Quiros-Guerrero L, Allard P, Nothias L, David B, Grondin A, Wolfender J
Sci Data
. 2024 Apr;
11(1):415.
PMID: 38649352
Natural products exhibit interesting structural features and significant biological activities. The discovery of new bioactive molecules is a complex process that requires high-quality metabolite profiling data to properly target the...
3.
Nothias L, Schmid R, Garlet A, Cameron H, Leoty-Okombi S, Andre-Frei V, et al.
mSystems
. 2024 Jan;
9(2):e0035623.
PMID: 38206014
Although metabolomics data acquisition and analysis technologies have become increasingly sophisticated over the past 5-10 years, deciphering a metabolite's function from a description of its structure and its abundance in...
4.
Bittremieux W, Avalon N, Thomas S, Kakhkhorov S, Aksenov A, Gomes P, et al.
Nat Commun
. 2023 Dec;
14(1):8488.
PMID: 38123557
Despite the increasing availability of tandem mass spectrometry (MS/MS) community spectral libraries for untargeted metabolomics over the past decade, the majority of acquired MS/MS spectra remain uninterpreted. To further aid...
5.
Wolfender J, Gaudry A, Rutz A, Quiros-Guerrero L, Nothias L, Queiroz E, et al.
Chimia (Aarau)
. 2023 Dec;
76(11):954-963.
PMID: 38069791
Metabolomics is playing an increasingly prominent role in chemical ecology and in the discovery of bioactive natural products (NPs). The identification of metabolites is a common/central objective in both research...
6.
Kim H, Zhang C, Reher R, Wang M, Alexander K, Nothias L, et al.
J Cheminform
. 2023 Aug;
15(1):71.
PMID: 37550756
The identification of molecular structure is essential for understanding chemical diversity and for developing drug leads from small molecules. Nevertheless, the structure elucidation of small molecules by Nuclear Magnetic Resonance...
7.
Schmid R, Heuckeroth S, Korf A, Smirnov A, Myers O, Dyrlund T, et al.
Nat Biotechnol
. 2023 Mar;
41(4):447-449.
PMID: 36859716
No abstract available.
8.
Shaffer J, Nothias L, Thompson L, Sanders J, Salido R, Couvillion S, et al.
Nat Microbiol
. 2022 Nov;
7(12):2128-2150.
PMID: 36443458
Despite advances in sequencing, lack of standardization makes comparisons across studies challenging and hampers insights into the structure and function of microbial communities across multiple habitats on a planetary scale....
9.
Quiros-Guerrero L, Nothias L, Gaudry A, Marcourt L, Allard P, Rutz A, et al.
Front Mol Biosci
. 2022 Nov;
9:1028334.
PMID: 36438653
Collections of natural extracts hold potential for the discovery of novel natural products with original modes of action. The prioritization of extracts from collections remains challenging due to the lack...
10.
Gaudry A, Huber F, Nothias L, Cretton S, Kaiser M, Wolfender J, et al.
Front Bioinform
. 2022 Oct;
2:842964.
PMID: 36304329
In natural products research, chemodiverse extracts coming from multiple organisms are explored for novel bioactive molecules, sometimes over extended periods. Samples are usually analyzed by liquid chromatography coupled with fragmentation...